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William L. Young
Researcher at University of California, San Francisco
Publications - 360
Citations - 19575
William L. Young is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Angiogenesis & Cerebral blood flow. The author has an hindex of 76, co-authored 359 publications receiving 17740 citations. Previous affiliations of William L. Young include University of California & Columbia University.
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Journal ArticleDOI
Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial
Jay P. Mohr,Michael K. Parides,Christian Stapf,Christian Stapf,Ellen Moquete,Claudia S. Moy,Jessica Overbey,Rustam Al-Shahi Salman,Eric Vicaut,William L. Young,Emmanuel Houdart,Charlotte Cordonnier,Marco Antonio Stefani,Andreas Hartmann,Rüdiger von Kummer,Alessandra Biondi,Joachim Berkefeld,Catharina J.M. Klijn,Kirsty Harkness,Richard B. Libman,Xavier Barreau,Alan J. Moskowitz +21 more
TL;DR: The ARUBA trial showed that medical management alone is superior to medical management with interventional therapy for the prevention of death or stroke in patients with unruptured brain arteriovenous malformations followed up for 33 months.
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Recommendations for the Management of Intracranial Arteriovenous Malformations A Statement for Healthcare Professionals From a Special Writing Group of the Stroke Council, American Stroke Association
Christopher S. Ogilvy,Philip E. Stieg,Issam A. Awad,Robert D. Brown,Douglas Kondziolka,Robert H. Rosenwasser,William L. Young,George J. Hademenos +7 more
TL;DR: Recommendations in this report represent an overview of existing treatment protocols that may vary considerably and serve as a basis for the development of treatment strategies for AVMs, which overall represent a fairly heterogeneous group of cerebrovascular lesions and which may demonstrate different natural histories.
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Aneurysm Growth Occurs at Region of Low Wall Shear Stress. Patient-Specific Correlation of Hemodynamics and Growth in a Longitudinal Study
Loic Boussel,Vitaliy L. Rayz,Charles E. McCulloch,Alastair J. Martin,Gabriel Acevedo-Bolton,Michael T. Lawton,Randall T. Higashida,Wade S. Smith,William L. Young,David Saloner +9 more
TL;DR: The results indicate that aneurysm growth is likely to occur in regions where the endothelial layer lining the vessel wall is exposed to abnormally low wall shear stress.
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Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts.
Craig Hashi,Yiqian Zhu,Guo-Yuan Yang,William L. Young,Benjamin S. Hsiao,Karin Wang,Benjamin Chu,Song Li +7 more
TL;DR: Several favorable characteristics of nanofibrous scaffolds, the excellent patency of small-diameter nan ofibrous vascular grafts, and the unique antithrombogenic property of MSCs are demonstrated.
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A supplementary grading scale for selecting patients with brain arteriovenous malformations for surgery.
TL;DR: This new AVM grading system supplements rather than replaces the well-established Spetzler-Martin grading system and is a better predictor of neurologic outcomes after AVM surgery.