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William M. Mikkelsen

Researcher at University of Michigan

Publications -  29
Citations -  7362

William M. Mikkelsen is an academic researcher from University of Michigan. The author has contributed to research in topics: Uric acid & Hyperuricemia. The author has an hindex of 17, co-authored 29 publications receiving 6856 citations. Previous affiliations of William M. Mikkelsen include United States Public Health Service.

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The distribution of serum uric acid values in a population unselected as to gout or hyperuricemia: tecumseh, michigan 1959-1960.

TL;DR: The data with reference to relative distribution above arbitrarily defined cutting points suggest that these points, commonly used in clinical medicine to define "hyperuricemia," are unrealistically low and, in addition, fail to take into account important differences associated with age.
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Estimates of the prevalence of rheumatic diseases in the population of Tecumseh, Michigan, 1959-60.

TL;DR: The latex fixation test performed poorly as a case detection tool, only one-third of those respondents with positive tests having any other evidence to suggest a diagnosis of rheumatoid arthritis, and rates of latex positively occurred in individuals with a history of jaundice or infectious hepatitis and in those with evidence of emphysema or right heart failure.
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The relationship of serum uric acid to risk factors in coronary heart disease

TL;DR: Analysis of the uric acid data from the initial examination cycle of the Tecumseh Community Health Study reveals that not only age and sex but also body weight or build should be considered when evaluating serum uric Acid levels in disease or relating serum Uric acid levels to other physiologic variables.
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Age-sex specific prevalence of radiographic abnormalities of the joints of the hands, wrists and cervical spine of adult residents of the tecumseh, michigan, community health study area, 1962-1965*

TL;DR: Those of post traumatic changes, including amputation of digits, in the hands and wrists and fusion of cervical vertebral bodies, thought to represent a failure of segmentation in embryonic life, were most frequent in residents of Tecumseh, Michigan.