W
William J. Koopman
Researcher at University of Alabama at Birmingham
Publications - 235
Citations - 19653
William J. Koopman is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Rheumatoid arthritis & Antibody. The author has an hindex of 55, co-authored 235 publications receiving 18847 citations. Previous affiliations of William J. Koopman include Veterans Health Administration & Albert Einstein College of Medicine.
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Journal ArticleDOI
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more
TL;DR: Variables from the medical history, physical examination, laboratory tests, and radiographs were used to develop sets of criteria that serve different investigative purposes and these proposed criteria utilize classification trees, or algorithms.
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The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip.
Roy D. Altman,Graciela S. Alarcón,D. Appelrouth,Daniel Bloch,David G. Borenstein,Kenneth D. Brandt,C. Brown,Cooke Td,W W Daniel,D. Feldman,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,Robert W. Ike,P. Kapila,David L. Kaplan,William J. Koopman,Catherine Marino,Eric V. McDonald,Dennis J. McShane,Thomas A. Medsger,B. A. Michel,William A. Murphy,T. Osial,Rosalind Ramsey-Goldman,Bruce M. Rothschild,Frederick Wolfe +26 more
TL;DR: Clinical criteria for the classification of symptomatic idiopathic (primary) osteoarthritis of the hands were developed from data collected in a multicenter study and required that at least 3 of these 4 criteria be present to classify a patient as having OA of the hand.
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Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.
Larry W. Moreland,Scott Baumgartner,Michael Schiff,Elizabeth A. Tindall,Roy Fleischmann,Arthur L. Weaver,Robert E. Ettlinger,Stanley Cohen,William J. Koopman,Kendall Mohler,Michael B. Widmer,Consuelo M. Blosch +11 more
TL;DR: In this three-month trial TNFR:Fc was safe, well tolerated, and associated with improvement in the inflammatory symptoms of rheumatoid arthritis.
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Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
Kimihisa Ichikawa,Weimin Liu,Limin Zhao,Zheng Wang,Di Liu,Toshiaki Ohtsuka,Huang-Ge Zhang,John D. Mountz,William J. Koopman,Robert P. Kimberly,Tong Zhou +10 more
TL;DR: It is shown here that elevated levels of cell-surface expression of DR5 and increased susceptibility to DR5-mediated apoptosis are characteristics of malignant tumor cells and selective, specific targeting ofDR5 with an agonistic antibody might be a safe and effective strategy for cancer therapy.
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Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.
Kenneth W. Beagley,John H. Eldridge,F Lee,Hiroshi Kiyono,Michael P. Everson,William J. Koopman,Toshio Hirano,Tadamitsu Kishimoto,Jerry R. McGhee +8 more
TL;DR: It is concluded that IL-6 plays an important role in promoting the terminal differentiation of PP B cells to IgA-secreting plasma cells and in inducing a sharp increase in numbers of B cells secreting IgA.