W
William R. Drobyski
Researcher at Medical College of Wisconsin
Publications - 158
Citations - 9950
William R. Drobyski is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Transplantation & Graft-versus-host disease. The author has an hindex of 47, co-authored 153 publications receiving 9243 citations. Previous affiliations of William R. Drobyski include University of Michigan & Texas Oncology.
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Journal ArticleDOI
Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.
Robert H. Collins,Ofer Shpilberg,William R. Drobyski,D L Porter,Sergio Giralt,R Champlin,S A Goodman,S N Wolff,W Hu,Catherine M. Verfaillie,Alan F. List,William S. Dalton,N Ognoskie,Angela Chetrit,Joseph H. Antin,John Nemunaitis +15 more
TL;DR: DLI results in complete remissions in a high percentage of patients with relapsed chronic-phase CML, and acute and chronic GVHD post-DLI were highly correlated with disease response (P < .00001).
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Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction
Yvonne H. Datta,Paul T. Adams,William R. Drobyski,Stephen P. Ethier,Valeri H. Terry,Mark S. Roth +5 more
TL;DR: RT-PCR of K19 is a sensitive, specific, and rapid method for detection of occult mammary carcinoma cells in the peripheral blood and bone marrow of patients with breast cancer and may be useful in diagnosing metastatic disease, as well as in monitoring the effectiveness of systemic therapy.
Journal ArticleDOI
Increasing Incidence of Adenovirus Disease in Bone Marrow Transplant Recipients
Phyllis Flomenberg,J Babbitt,William R. Drobyski,R C Ash,D R Carrigan,G V Sedmak,Timothy L. McAuliffe,Bruce M. Camitta,Mary M. Horowitz,Nancy Bunin +9 more
TL;DR: A higher incidence of both adenovirus infection and disease than do previous studies is documents, and Adenovirus may emerge as a more frequent pathogen as more high-risk BMT transplants are done.
Journal ArticleDOI
Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: efficacy and toxicity of a defined T-cell dose
William R. Drobyski,Keever C,Roth,S Koethe,Gerald A. Hanson,P McFadden,Jerome L. Gottschall,Robert C. Ash,P. Van Tuinen,Mary M. Horowitz +9 more
TL;DR: It is demonstrated that leukocyte infusions that administered a defined T-cell dose can exert a profound graft-versus- leukemia effect and are an effective form of salvage immunotherapy in allogeneic marrow transplant recipients.
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Fatal Encephalitis Due to Variant B Human Herpesvirus-6 Infection in a Bone Marrow-Transplant Recipient
TL;DR: Human herpesvirus-6 is the causative agent of exanthem subitum and febrile illnesses in children and has been implicated in interstitial pneumonitis, and bone marrow suppression after transplantation, and the pathogenicity of HHV-6 has yet to be fully delineated in either immunocompetent or Immunocompromised hosts.