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William Wallace
Researcher at Royal Hospital for Sick Children
Publications - 166
Citations - 11429
William Wallace is an academic researcher from Royal Hospital for Sick Children. The author has contributed to research in topics: Fertility preservation & Cancer. The author has an hindex of 50, co-authored 159 publications receiving 10261 citations. Previous affiliations of William Wallace include Air Force Research Laboratory & University of Edinburgh.
Papers
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Journal ArticleDOI
Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.
David J. Porteous,Julia R. Dorin,Gerry McLachlan,H Davidson-Smith,Heather Davidson,Barbara J Stevenson,A D Carothers,William Wallace,S Moralee,C Hoenes,G Kallmeyer,U Michaelis,K Naujoks,Ling-Pei Ho,J M Samways,M. Imrie,Andrew P. Greening,J A Innes +17 more
TL;DR: The level of gene transfer and functional correction were comparable to those reported previously using adenoviral vectors or another DNA–liposome complex, but here were sustained and uncompromised by false positives.
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How do chemotherapeutic agents damage the ovary
TL;DR: It is likely that different chemotherapeutic drugs act through a range of mechanisms and on different target cells, and more research into the cellular mechanisms underpinning chemotherapy-induced follicle loss could lead to the generation of treatments specifically designed to prevent POF.
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Depletion of ovarian reserve in young women after treatment for cancer in childhood: detection by anti‐Müllerian hormone, inhibin B and ovarian ultrasound
TL;DR: Both hormonal and biophysical evidence of partial loss of the ovarian reserve in young cancer survivors was detected both in women with normal menstrual cycles and during COCP administration.
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Endobronchial and endoscopic ultrasound-guided real-time fine-needle aspiration for mediastinal staging.
Robert C. Rintoul,Kristopher M. Skwarski,John T. Murchison,William Wallace,Warren Walker,Ian D. Penman +5 more
TL;DR: Endobronschial ultrasound with real-time transbronchial needle aspiration offers improved sensitivity and accuracy for staging of the middle mediastinum, and, combined with endoscopic ultrasound, should allow investigation of the majority of the mediastInum.
Journal ArticleDOI
Human ovarian reserve from conception to the menopause
William Wallace,Tom Kelsey +1 more
TL;DR: The best fitting model for the establishment and decline of human NGF is described and the rate of NGF recruitment into growing follicles for all women increases from birth until approximately age 14 years (coinciding with puberty) then decreases towards the menopause.