W
Wim H. Scheele
Researcher at Pfizer
Publications - 10
Citations - 1775
Wim H. Scheele is an academic researcher from Pfizer. The author has contributed to research in topics: Osteoporosis & Bone density. The author has an hindex of 9, co-authored 10 publications receiving 1665 citations. Previous affiliations of Wim H. Scheele include Eli Lilly and Company.
Papers
More filters
Journal ArticleDOI
The effect of teriparatide [human parathyroid hormone (1-34)] therapy on bone density in men with osteoporosis.
Eric S. Orwoll,Wim H. Scheele,S Paul,S. Adami,Unni Syversen,Adolfo Diez-Perez,JM Kaufman,A D Clancy,Gregory A Gaich +8 more
TL;DR: It is shown that teriparatide treatment results in an increase in bone mineral density and is a potentially useful therapy for osteoporosis in men.
Journal ArticleDOI
A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis.
Jean-Jacques Body,Gregory A Gaich,Wim H. Scheele,Pandurang M. Kulkarni,Paul D. Miller,Anne Peretz,Robin K. Dore,Ricardo Correa-Rotter,Alexandra Papaioannou,David C. Cumming,Anthony B. Hodsman +10 more
TL;DR: Teriparatide, a bone formation agent, increased BMD at most sites and decreased nonvertebral fractures more than alendronate in 146 postmenopausal women with osteoporosis.
Journal ArticleDOI
Sustained vertebral fracture risk reduction after withdrawal of teriparatide in postmenopausal women with osteoporosis.
Robert Lindsay,Wim H. Scheele,Robert M. Neer,Gerhardt Pohl,Silvano Adami,Carlos Mautalen,Jean-Yves Reginster,Jan J. Stepan,Stephen L. Myers,Bruce H. Mitlak +9 more
TL;DR: Vertebral fracture risk reduction by teriparatide administration persists for at least 18 months after discontinuation of therapy, and post hoc analysis suggests that teripararatide treatment substantially reduced the increased risk of subsequent fracture in women who sustained a fracture during the FPT.
Journal ArticleDOI
Additive Effects of Raloxifene and Alendronate on Bone Density and Biochemical Markers of Bone Remodeling in Postmenopausal Women with Osteoporosis
TL;DR: RLX+ALN reduced bone turnover more than either drug alone, resulting in greater BMD increment, but whether this difference reflects better fracture risk reduction was not assessed in this study.
Journal ArticleDOI
Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis.
Jörg Goldhahn,Wim H. Scheele,Bruce H. Mitlak,Eric Abadie,Per Aspenberg,Peter Augat,Maria-Luisa Brandi,Nansa Burlet,Arkadi Chines,Pierre D. Delmas,Isabelle Dupin-Roger,D Ethgen,Beate P. Hanson,F. Hartl,John A. Kanis,Reshma Kewalramani,Andrea Laslop,David Marsh,S. Ormarsdottir,René Rizzoli,Art Santora,Gerhard Schmidmaier,Michael Wagener,Jean-Yves Reginster +23 more
TL;DR: A consensus process was initiated to provide recommendations for the clinical evaluation of potential therapies to augment fracture repair in patients with meta- and diaphyseal fractures.