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Wolfgang Kresse
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 6
Citations - 391
Wolfgang Kresse is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Zinc & Intracellular. The author has an hindex of 6, co-authored 6 publications receiving 361 citations. Previous affiliations of Wolfgang Kresse include Free University of Berlin.
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Acute Insult of Ammonia Leads to Calcium-dependent Glutamate Release from Cultured Astrocytes, an Effect of pH
TL;DR: It is indicated that an acute exposure to ammonia, resulting in cytosolic alkalinization, leads to calcium-dependent glutamate release from astrocytes, which could contribute to glutamate dysfunction consistently observed in acute HE.
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ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc
Christiane Nolte,Ariel Gore,Israel Sekler,Wolfgang Kresse,Michal Hershfinkel,Anja Hoffmann,Helmut Kettenmann,Arie Moran +7 more
TL;DR: Induction of ZnT‐1 may play a protective role when mild episodes of stroke or seizures are followed by a massive brain insult, indicating that preconditioning protects astrocytes from zinc toxicity.
ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc [Erratum in: Glia. vol 48, pg 346, 2004]
Christiane Nolte,Ariel Gore,Israel Sekler,Wolfgang Kresse,Michal Hershfinkel,Anja Hoffmann,Helmut Kettenmann,Arie Moran +7 more
TL;DR: In this paper, the role of ZnT-1 in reducing zinc-dependent cell damage in astrocytes was assessed, and the effect of pre-treatment with sub-lethal concentrations of zinc was demonstrated.
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DMACM-Caged Adenosine Nucleotides: Ultrafast Phototriggers for ATP, ADP, and AMP Activated by Long-Wavelength Irradiation†
Daniel Geissler,Wolfgang Kresse,Burkhard Wiesner,Jürgen Bendig,Helmut Kettenmann,Volker Hagen +5 more
TL;DR: The development of new photocleavable adenosine nucleotides based on the photochemistry of [7‐(dimethylamino)coumarin‐4‐yl]methyl (DMACM) esters is described and the effect of photoreleased ATP on the cellular response of astrocytes, namely the ability of the ATP to evoke Ca2+ ion waves is measured.
Journal ArticleDOI
Zinc ions are endogenous modulators of neurotransmitter-stimulated capacitative Ca2+ entry in both cultured and in situ mouse astrocytes.
Wolfgang Kresse,Israel Sekler,Anja Hoffmann,Oliver Peters,Christiane Nolte,Arie Moran,Helmut Kettenmann +6 more
TL;DR: It is concluded that zinc, which is coreleased from glutamatergic synaptic vesicles upon neuronal activity, has a major impact on shaping the astrocytic calcium responses.