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Daniel Geissler
Researcher at Max Planck Society
Publications - 7
Citations - 535
Daniel Geissler is an academic researcher from Max Planck Society. The author has contributed to research in topics: Transgene & Gene. The author has an hindex of 7, co-authored 7 publications receiving 499 citations. Previous affiliations of Daniel Geissler include Humboldt State University & Leibniz Association.
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Journal ArticleDOI
Mechanism of Photocleavage of (Coumarin-4-yl)methyl Esters
TL;DR: In this paper, the results of photostationary and time-resolved investigations of 25 CM−A esters and corresponding CM−OH alcohols with varying substitution on the (coumarin-4-yl)methyl moiety and a wide variation in the structure of the acidic part have been analyzed.
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Coumarinylmethyl esters for ultrafast release of high concentrations of cyclic nucleotides upon one- and two-photon photolysis.
Volker Hagen,Brigitte Dekowski,Vasilica Nache,Reinhard Schmidt,Daniel Geissler,Dorothea Lorenz,Jenny Eichhorst,Sandro Keller,Hiroshi Kaneko,Klaus Benndorf,Burkhard Wiesner +10 more
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(Coumarin‐4‐yl)methyl Esters as Highly Efficient, Ultrafast Phototriggers for Protons and Their Application to Acidifying Membrane Surfaces
Daniel Geissler,Yuri N. Antonenko,Reinhard Schmidt,Sandro Keller,Oxana O. Krylova,Burkhard Wiesner,Jürgen Bendig,Peter Pohl,Volker Hagen +8 more
TL;DR: With these proton sources (“caged protons”), the spatial and temporal pH distribution can be controlled without diffusional mixing delays, and a new class of phototriggers for protons that facilitates the study of proton-dependent biological processes is introduced.
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Doxycycline-dependent photoactivated gene expression in eukaryotic systems
Sidney B. Cambridge,Sidney B. Cambridge,Daniel Geissler,Daniel Geissler,Federico Calegari,Konstantinos Anastassiadis,Mazahir T. Hasan,A. Francis Stewart,Wieland B. Huttner,Volker Hagen,Tobias Bonhoeffer +10 more
TL;DR: Two reversibly inhibited, photoactivatable ('caged') doxycycline derivatives with different membrane permeabilities are synthesized for precise spatial and temporal light-controlled activation of transgenes based on the 'Tet-on' system for high-resolution conditional transgene expression at different spatial scales.
Journal ArticleDOI
A Caged Doxycycline Analogue for Photoactivated Gene Expression
TL;DR: A photosensitive (“caged”) doxycycline analogue is synthesized for precise light-controlled activation of genes based on the “Tet-on” (Tet= tetracycline) system to improve the resolution of transgene expression.