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Wouter A. van der Heijden

Researcher at Radboud University Nijmegen

Publications -  20
Citations -  230

Wouter A. van der Heijden is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 12 publications receiving 126 citations.

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Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin.

TL;DR: The findings that ~8% of Tregs in the circulation of healthy individuals are CD41(+)P-selectin(+) and that distinct binding of patient plasma PMPs to T Regs was observed support in vivo relevance, opening the exciting possibility that PMPs actively regulate the immune response at sites of (vascular) inflammation.
Journal ArticleDOI

Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study.

TL;DR: Treatment, but not prophylaxis, with low-dose acetylsalicylic acid, partially reverses endotoxin tolerance in humans in vivo by shifting response toward a proinflammatory phenotype.