W
Wynn Legon
Researcher at University of Virginia
Publications - 38
Citations - 2430
Wynn Legon is an academic researcher from University of Virginia. The author has contributed to research in topics: Somatosensory evoked potential & Neuromodulation (medicine). The author has an hindex of 19, co-authored 35 publications receiving 1682 citations. Previous affiliations of Wynn Legon include Virginia Tech & University of Minnesota.
Papers
More filters
Journal ArticleDOI
Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans
Wynn Legon,Tomokazu F. Sato,Alexander Opitz,Jerel K. Mueller,Aaron J. Barbour,Amanda J. Williams,William J. Tyler +6 more
TL;DR: It is concluded that transcranial focused ultrasound (tFUS) targeted to the human primary somatosensory cortex can be used to focally modulate human cortical function.
Journal ArticleDOI
Neuromodulation with single-element transcranial focused ultrasound in human thalamus.
TL;DR: TFUS targeted at unilateral sensory thalamus inhibited the amplitude of the P14 SEP as compared to sham, and there is evidence of translation of this effect to time windows of the EEG commensurate with SI and SII activities.
Journal ArticleDOI
Transcranial focused ultrasound neuromodulation of the human primary motor cortex
TL;DR: This is the first report of the effect of ultrasound on human motor cortical excitability and motor behavior and confirms previous results in the somatosensory cortex that ultrasound results in effective neuronal inhibition that confers a performance advantage.
Journal ArticleDOI
Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway
Hongsun Guo,Mark Hamilton,Sarah J. Offutt,Cory D. Gloeckner,Tianqi Li,Yohan Kim,Wynn Legon,Wynn Legon,Jamu K. Alford,Hubert H. Lim +9 more
TL;DR: These findings indicate that US activates the ascending auditory system through a cochlear pathway, which can activate other non-auditory regions through cross-modal projections, which challenges the idea that US can directly activate neurons in the intact brain.
Journal ArticleDOI
Physiological observations validate finite element models for estimating subject-specific electric field distributions induced by transcranial magnetic stimulation of the human motor cortex.
TL;DR: Differences between electric field computations estimated using the finite element method (FEM) and projection-based approaches to account for variations in gyral folding patterns and tissue conductivity anisotropy are inspected to help improve the targeting accuracy of TMS in the mapping or modulation of human brain circuits.