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Xiang-Fu Wu
Researcher at University of Toronto
Publications - 2
Citations - 4241
Xiang-Fu Wu is an academic researcher from University of Toronto. The author has contributed to research in topics: Signal peptide & Glycoprotein. The author has an hindex of 2, co-authored 2 publications receiving 4130 citations. Previous affiliations of Xiang-Fu Wu include Canadian Red Cross.
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Journal ArticleDOI
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice.
Fouad Shalaby,Janet Rossant,Janet Rossant,Terry P. Yamaguchi,Terry P. Yamaguchi,Marina Gertsenstein,Xiang-Fu Wu,Xiang-Fu Wu,Martin L. Breitman,Martin L. Breitman,Andre C. Schuh +10 more
TL;DR: The generation of mice deficient in Flk-1 by disruption of the gene using homologous recombination in embryonic stem (ES) cells is reported, indicating that FlK-1 is essential for yolk-sac blood-island formation and vasculogenesis in the mouse embryo.
Journal ArticleDOI
Cell surface antigen CD109 is a novel member of the α2 macroglobulin/C3, C4, C5 family of thioester-containing proteins
Martin Lin,D. Robert Sutherland,Wendy Horsfall,Nicholas F. Totty,Erik Yeo,Rakash Nayar,Xiang-Fu Wu,Andre C. Schuh +7 more
TL;DR: Not only is CD109 potentially capable of covalent binding to carbohydrate and protein targets, but the t(1/2) of its activated thioester is likely extremely short, indicating that CD109 action is highly restricted spatially to the site of its activation.