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Xiangrui Meng
Researcher at Zhengzhou University
Publications - 18
Citations - 157
Xiangrui Meng is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 7 publications receiving 107 citations.
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Journal ArticleDOI
MicroRNA-202 inhibits tumor progression by targeting LAMA1 in esophageal squamous cell carcinoma.
TL;DR: Findings suggest that miR-202 may function as a novel tumor suppressor in ESCC by repressing cell proliferation and migration, and its biological effects may attribute the inhibition of LAMA1-mediated FAK-PI3K-Akt signaling.
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Transcriptional regulatory networks in human lung adenocarcinoma.
TL;DR: The objective of the study was to interpret the mechanisms of human AC through the regulatory network using the GSE2514 microarray data and it appears that PPARG promotes the PPAR signaling pathway via the upregulation of lipoprotein, but suppresses the cell cycle pathway via downregulation.
Journal ArticleDOI
Camrelizumab plus apatinib as second-line treatment for advanced oesophageal squamous cell carcinoma (CAP 02): a single-arm, open-label, phase 2 trial.
Xiangrui Meng,Tao Wu,Yong Jin Hong,Qing-xia Fan,Zhonghai Ren,Yanzhen Guo,Xiuli Yang,Pei-na Shi,Jiamei Yang,Xianzhe Yin,Zhi-Yu Luo,Jin Xia,Yue Zhou,Mengli Xu,Enjie Liu,Guozhong Jiang,Shenglei Li,Feng Zhao,Chi Ma,Chuanxiang Ma,Zhiguo Hou,Jing Li,Junsheng Wang,Feng Wang +23 more
TL;DR: Wang et al. as mentioned in this paper evaluated the combination of camrelizumab and apatinib as second-line treatment for advanced oesophageal squamous cell carcinoma.
Journal ArticleDOI
Expression analysis of miRNA and target mRNAs in esophageal cancer.
TL;DR: Differentially expressed miRNAs and related mRNAs mainly involved in cancer-related and signal-transduction pathways and Functional categories of these target genes were related to transcriptional regulation.
Journal ArticleDOI
miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2.
TL;DR: In this paper, the authors demonstrate the role of miR-202 in regulating ESCC cell apoptosis and identify HSF2 as a direct target with the binding site on the 3'-UTR of HSF 2 mRNA in ESCC cells.