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Xiangwei Gao
Researcher at Zhejiang University
Publications - 41
Citations - 2265
Xiangwei Gao is an academic researcher from Zhejiang University. The author has contributed to research in topics: Angiogenin & Translation (biology). The author has an hindex of 20, co-authored 33 publications receiving 1748 citations. Previous affiliations of Xiangwei Gao include Cornell University.
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Dynamic m6A mRNA methylation directs translational control of heat shock response
TL;DR: The elucidation of the dynamic features of 5′UTR methylation and its critical role in cap-independent translation not only expands the breadth of physiological roles of m6A, but also uncovers a previously unappreciated translational control mechanism in heat shock response.
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Mechanisms of action of angiogenin
Xiangwei Gao,Zhengping Xu +1 more
TL;DR: Angiogenin has neuroprotective activities in the central nervous system and the loss of its function may be related to amyotrophic lateral sclerosis.
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Quantitative profiling of initiating ribosomes in vivo
TL;DR: In this article, the authors present quantitative translation initiation sequencing (QTI-seq), with which the initiating ribosomes can be profiled in real time at single-nucleotide resolution.
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The Induction of Yes-Associated Protein Expression After Arterial Injury Is Crucial for Smooth Muscle Phenotypic Modulation and Neointima Formation
Xiaobo Wang,Guoqing Hu,Xiangwei Gao,Yong Wang,Wei Zhang,Erin Y. Harmon,Xu Zhi,Zhengping Xu,Michelle R. Lennartz,Margarida Barroso,Mohamed Trebak,Ceshi Chen,Jiliang Zhou +12 more
TL;DR: YAP plays a novel integrative role in SM phenotypic modulation by inhibiting SM-specific gene expression while promoting SM proliferation and migration in vitro and in vivo.
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YTHDF1-mediated translation amplifies Wnt-driven intestinal stemness
Bing Han,Sujun Yan,Saisai Wei,Jie Xiang,Kangli Liu,Zhanghui Chen,Rongpan Bai,Jinghao Sheng,Zhengping Xu,Xiangwei Gao +9 more
TL;DR: YTHDF1, an m6A reader, is highly expressed in ISCs and its expression is upregulated by Wnt signaling at the translational level, which is required for the maintenance of ISCs during regeneration and tumorigenesis.