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Shu-Bing Qian

Researcher at Cornell University

Publications -  86
Citations -  13397

Shu-Bing Qian is an academic researcher from Cornell University. The author has contributed to research in topics: Translation (biology) & Ribosome profiling. The author has an hindex of 35, co-authored 79 publications receiving 10438 citations. Previous affiliations of Shu-Bing Qian include University of North Carolina at Chapel Hill & Peking University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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5′ UTR m6A Promotes Cap-Independent Translation

TL;DR: It is shown that mRNAs containing N(6)-methyladenosine (m(6)A) in their 5' UTR can be translated in a cap-independent manner, and that diverse cellular stresses induce a transcriptome-wide redistribution of m( 6)A, resulting in increased numbers of m RNAs with 5'UTR m(6), which bypasses 5' cap-binding proteins to promote translation under stresses.
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Dynamic m6A mRNA methylation directs translational control of heat shock response

TL;DR: The elucidation of the dynamic features of 5′UTR methylation and its critical role in cap-independent translation not only expands the breadth of physiological roles of m6A, but also uncovers a previously unappreciated translational control mechanism in heat shock response.
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Decoding Human Cytomegalovirus

TL;DR: The results reveal an unanticipated complexity to the HCMV coding capacity and illustrate the role of regulated changes in transcript start sites in generating this complexity.