Xiao-Lu Chen

TL;DR: Anti-TNFα (infliximab, a potent clinically used drug) treatment significantly ameliorate endothelial necroptosis, BBB destruction and improve stroke outcomes and suggest infliximab might serve as a potential drug for stroke therapy.

TL;DR: It is suggested that microRNA‐150 could regulate claudin‐5 expression and endothelial cell survival by targeting Tie‐2, thus affecting the permeability of BBB after permanent middle cerebral artery occlusion in rats, and that miR‐150 might be a potential alternative target for the treatment of stroke.

TL;DR: This study reports a miR‐150‐based mechanism underlying cerebral poststroke angiogenesis, which is a harmonized target for poststroke recovery.

TL;DR: In this paper , the causal relationship between SIH and spontaneous intracerebral hemorrhage (ICH) was found to be a rare finding after DM secondary to pre-existing diabetes mellitus or stress-induced hyperglycemia.

TL;DR: The SIGNALS score reliably predicts the risk of in-hospital neurological deterioration of patients with intracerebral hemorrhage.