X
Xiao Peng Dai
Researcher at Chinese PLA General Hospital
Publications - 2
Citations - 742
Xiao Peng Dai is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: CD8 & Immune system. The author has an hindex of 2, co-authored 2 publications receiving 348 citations.
Papers
More filters
Journal ArticleDOI
Single-cell landscape of immunological responses in patients with COVID-19.
Ji Yuan Zhang,Xiang Ming Wang,Xudong Xing,Zhe Xu,Chao Zhang,Jin-Wen Song,Xing Fan,Peng Xia,Jun Liang Fu,Si Yu Wang,Ruo Nan Xu,Xiao Peng Dai,Lei Shi,Lei Huang,Tian Jun Jiang,Ming Shi,Yuxia Zhang,Alimuddin Zumla,Alimuddin Zumla,Markus Maeurer,Fan Bai,Fu-Sheng Wang +21 more
TL;DR: The single-cell transcriptional landscape of moderate, severe and convalescent cases of patients with COVID-19 describes the dynamic nature of immune responses during disease progression, and shows a deranged interferon response, profound immune exhaustion with skewed T cell receptor repertoire and broad T cell expansion.
Journal ArticleDOI
Immunological and inflammatory profiles in mild and severe cases of COVID-19.
Jin-Wen Song,Chao Zhang,Xing Fan,Fan Ping Meng,Zhe Xu,Peng Xia,Wen-Jing Cao,Wen-Jing Cao,Tao Yang,Xiao Peng Dai,Si Yu Wang,Ruo Nan Xu,Tian Jun Jiang,Wen Gang Li,Dawei Zhang,Peng Zhao,Ming Shi,Chiara Agrati,Giuseppe Ippolito,Markus Maeurer,Alimuddin Zumla,Fu-Sheng Wang,Ji Yuan Zhang +22 more
TL;DR: A higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild, indicate that immune-based targets for therapeutic interventions constitute a promising treatment for severe COVID-19 patients.