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Wen-Jing Cao
Researcher at Bengbu Medical College
Publications - 14
Citations - 881
Wen-Jing Cao is an academic researcher from Bengbu Medical College. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 5, co-authored 9 publications receiving 420 citations. Previous affiliations of Wen-Jing Cao include Chinese PLA General Hospital.
Papers
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Journal ArticleDOI
Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis.
Jin-Wen Song,Sin Man Lam,Xing Fan,Wen-Jing Cao,Si Yu Wang,He Tian,Gek Huey Chua,Chao Zhang,Fan Ping Meng,Zhe Xu,Jun Liang Fu,Lei Huang,Peng Xia,Tao Yang,Shaohua Zhang,Bowen Li,Tian Jun Jiang,Raoxu Wang,Zehua Wang,Ming Shi,Ji Yuan Zhang,Fu-Sheng Wang,Guanghou Shui +22 more
TL;DR: It is suggested that GM3-enriched exosomes may partake in pathological processes related to COVID-19 pathogenesis, and the largest repository on the plasma lipidome and metabolome distinct to CO VID-19 is presented.
Journal ArticleDOI
Immunological and inflammatory profiles in mild and severe cases of COVID-19.
Jin-Wen Song,Chao Zhang,Xing Fan,Fan Ping Meng,Zhe Xu,Peng Xia,Wen-Jing Cao,Wen-Jing Cao,Tao Yang,Xiao Peng Dai,Si Yu Wang,Ruo Nan Xu,Tian Jun Jiang,Wen Gang Li,Dawei Zhang,Peng Zhao,Ming Shi,Chiara Agrati,Giuseppe Ippolito,Markus Maeurer,Alimuddin Zumla,Fu-Sheng Wang,Ji Yuan Zhang +22 more
TL;DR: A higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild, indicate that immune-based targets for therapeutic interventions constitute a promising treatment for severe COVID-19 patients.
Journal ArticleDOI
Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies as a Serologic Marker of Infection in Patients With Coronavirus Disease 2019.
Zhao Rongqing,Maohua Li,Hao Song,Jianxin Chen,Wenlin Ren,Yingmei Feng,George F. Gao,Jin-Wen Song,Ya Peng,Bin Su,Xianghua Guo,Yanjun Wang,Jingong Chen,Jianli Li,Hunter Sun,Zhonghu Bai,Wen-Jing Cao,Jin Zhu,Qinlu Zhang,Yufei Sun,Sean Sun,Xinkun Mao,Junchi Su,Xiang Chen,Ailiang He,Wen Gao,Ronghua Jin,Yongzhong Jiang,Le Sun +28 more
TL;DR: With the assays developed here,medical staff, incoming patients, passengers, and people who are in close contact with the confirmed patients to identify the "innocent viral spreaders," protect the medical staff, and stop further spread of the virus.
Journal ArticleDOI
A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19.
Sin Man Lam,Chao Zhang,Zehua Wang,Zhen Ni,Shaohua Zhang,Siyuan Yang,Xiahe Huang,Lesong Mo,Jie Li,Bernett Lee,Mei Mei,Lei Huang,Ming Shi,Zhe Xu,Fanping Meng,Wen-Jing Cao,Wen-Jing Cao,Ming-Ju Zhou,Ming-Ju Zhou,Lei Shi,Gek Huey Chua,Bowen Li,Jiabao Cao,Jun Wang,Shilai Bao,Yingchun Wang,Jin-Wen Song,Fujie Zhang,Fu-Sheng Wang,Guanghou Shui +29 more
TL;DR: In this article, the authors conduct high-coverage lipidomics with an emphasis on sterols and oxysterols, and proteomic analyses of exosome-enriched extracellular vesicles (EVs hereafter) from patients at different temporal stages of COVID-19.
Posted ContentDOI
Serological diagnostic kit of SARS-CoV-2 antibodies using CHO-expressed full-length SARS-CoV-2 S1 proteins
Rongqing Zhao,Maohua Li,Hao Song,Jianxin Chen,Wenlin Ren,Yingmei Feng,Jin-Wen Song,Ya Peng,Bin Su,Xianghua Guo,Yanjun Wang,Jingong Chen,Jianli Li,Hunter Sun,Zhonghu Bai,Wen-Jing Cao,Jin Zhu,Qinlu Zhang,Yufei Sun,Sean Sun,Xinkun Mao,Junchi Su,Hui Chen,Ailiang He,Ronghua Jin,Le Sun +25 more
TL;DR: A COVID-19/SARS-CoV-2 S1 serology ELISA kit for the detection of total anti-virus antibody (IgG+IgM) titers in sera from either the general population or patients suspected to be infected is reported.