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Xiao Xie
Researcher at Shanghai Jiao Tong University
Publications - 13
Citations - 167
Xiao Xie is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 5, co-authored 13 publications receiving 76 citations.
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Journal ArticleDOI
GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling
Wen Lian Chen,Xing Jin,Mingsong Wang,Dan Liu,Qin Luo,Hechuan Tian,Lili Cai,Lifei Meng,Rui Bi,Lei Wang,Xiao Xie,Guanzhen Yu,Lihui Li,Changsheng Dong,Qiliang Cai,Wei Jia,Wenyi Wei,Lijun Jia +17 more
TL;DR: It is demonstrated that, under the condition of coexistence of metabolic fuels in the body, fructose was readily used by LC cells in vivo as a glucose alternative via upregulating GLUT5, a major fructose transporter encoded by solute carrier family 2 member 5 (SLC2A5).
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Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression.
Pei Xu,Lei Wang,Xiao Xie,Fengqing Hu,Qi Yang,Rui Hu,Lianyong Jiang,Fangbao Ding,Ju Mei,Jianhui Liu,Haibo Xiao +10 more
TL;DR: Present investigation discovered that hsa_circ_0001869 enhanced NSCLC progression via sponging miR-638 and promoting FOSL2 expression and downregulation suppressed tumor growth and invasion ability.
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Mitochondrial NDUFA4L2 protein promotes the vitality of lung cancer cells by repressing oxidative stress.
TL;DR: A better understanding of the mechanism of NDUFA4L2 in NSCLC survival in hypoxic environments is essential to design new therapeutic methods.
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Activated cdc42-associated kinase is up-regulated in non-small-cell lung cancer and necessary for FGFR-mediated AKT activation.
TL;DR: It was found that the expression of ACK1 was significantly up‐regulated in NSCLC samples compared to their adjacent normal tissues and the expression was inversely correlated with the survival ofNSCLC patients.
Journal ArticleDOI
TMEM45B, up-regulated in human lung cancer, enhances tumorigenicity of lung cancer cells
TL;DR: It is demonstrated that TMEM45B was overexpressed in lung cancer and its expression correlated with overall survival of patients and is a potential prognostic marker and cancer-selective therapeutic target in lung cancers.