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Xiao Yang Wang
Researcher at National Institutes of Health
Publications - 4
Citations - 342
Xiao Yang Wang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Progenitor cell & Stem cell. The author has an hindex of 3, co-authored 3 publications receiving 329 citations. Previous affiliations of Xiao Yang Wang include Georgetown University.
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Journal ArticleDOI
Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells.
TL;DR: An adenoviral vector-based expression system is utilized to demonstrate a protective role for p21(Waf1/Cip1) during PGA2 cellular stress and provide strong evidence that the implementation of cellular growth arrest contributes to this protective influence.
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Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways.
TL;DR: The results identify Msi1 as a key determinant of the mammary lineage through its ability to coordinate cell cycle entry and activate the Notch and Wnt pathways by a novel autocrine process involving PLF1 and DKK3.
Journal ArticleDOI
Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer.
Xiao Yang Wang,Huina Yu,R. Ilona Linnoila,Laodong Li,Dangyu Li,Biwen Mo,Hideyuki Okano,Luiz O. F. Penalva,Robert I. Glazer +8 more
TL;DR: Musashi1 (Msi1) was expressed in a diffuse pattern in most tumor subtypes, except in squamous cell carcinomas, where it appeared in a focal pattern in 50% of specimens, and is a sensitive and specific diagnostic marker for all lung cancer subtypes.
Journal ArticleDOI
A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish.
TL;DR: A novel homozygous missense variant (c.233A > G, p.Lys78Arg) in the OXR1 gene is reported, which was identified in a 4-year-old girl with sensorineural hearing loss (SNHL), hinting an important role of OxR1 and associated partners in cochlear development and hearing function.