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Xiaochuan Feng

Researcher at Tufts University

Publications -  26
Citations -  1438

Xiaochuan Feng is an academic researcher from Tufts University. The author has contributed to research in topics: Cryptosporidium parvum & Enterocytozoon bieneusi. The author has an hindex of 18, co-authored 26 publications receiving 1372 citations.

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Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda.

TL;DR: Mortality rates were higher among children with severe dehydration and persistent diarrhea, and in stunted or underweight children infected with C. parvum, which remains untreatable among Ugandan children.
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Cryptosporidiosis and microsporidiosis in ugandan children with persistent diarrhea with and without concurrent infection with the human immunodeficiency virus

TL;DR: Only HIV status was independently associated with either Cryptosporidium or E. bieneusi, with HIV being the only independent predictor of coinfection in children with PD, with and without HIV/AIDS attending Mulago National Referral Hospital.
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Genomic survey of the non-cultivatable opportunistic human pathogen, Enterocytozoon bieneusi

TL;DR: The findings suggest that E. bieneusi is a likely model for extreme genome reduction and host dependence, and short intergenic regions, high gene density, and shortened protein-coding sequences were observed in the E. biosporidian genome, all traits consistent with genomic compaction.
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Animal propagation and genomic survey of a genotype 1 isolate of Cryptosporidium parvum

TL;DR: A type 1 isolate, obtained from an individual with HIV and cryptosporidiosis, was successfully adapted to propagate in gnotobiotic piglets, which should facilitate characterization of the unique features of this human pathogen.
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Infectivity of a Cryptosporidium parvum Isolate of Cervine Origin for Healthy Adults and Interferon-γ Knockout Mice

TL;DR: The infectivity of a Cryptosporidium parvum isolate of cervine origin (type 2, Moredun) propagated in calves was investigated simultaneously in healthy adult human volunteers and in interferon-gamma knockout (GKO) mice for discerning isolate-specific differences in pathogenicity.