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Xiaofang Guo
Researcher at University of South Florida
Publications - 29
Citations - 1167
Xiaofang Guo is an academic researcher from University of South Florida. The author has contributed to research in topics: Nasopharyngeal carcinoma & Medicine. The author has an hindex of 17, co-authored 21 publications receiving 1017 citations. Previous affiliations of Xiaofang Guo include Changsha Medical University & Chinese Ministry of Education.
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Journal ArticleDOI
miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2.
Lipeng Liu,Xiaohua Yu,Xiaofang Guo,Zhi Tian,Su Min,Yu Long,Huang Chunxia,Feng Zhou,Liu Meiling,Xinhua Wu,Xiaochun Wang +10 more
TL;DR: Direct involvement in the regulation of Bcl-2 may be one of the mechanisms through which miR-143 may play a role in the pathogenesis of cervical cancer.
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miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma
Min Deng,Hailin Tang,Hailin Tang,Yanhong Zhou,Ming Zhou,Wei Xiong,Ying Zheng,Qiurong Ye,Xi Zeng,Xi Zeng,Qianjin Liao,Qianjin Liao,Xiaofang Guo,Xiaoling Li,Jian Ma,Guiyuan Li +15 more
TL;DR: The present study found that miR-216b was downregulated in nasopharyngeal carcinoma (NPC) cell lines and specimens and demonstrated that it can bind to the 3′ untranslated region (UTR) of KRAS and inhibit expression of the KRAS protein.
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LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation
Qianjin Liao,ZhaoYang Y. Zeng,Xiaofang Guo,XiaYu Y. Li,Fang Wei,W Zhang,Pan Chen,Fang Liang,Bo Xiang,Jian Ma,Min Wu,Haosheng Tang,Min Deng,Xi Zeng,Ke Tang,Wei Xiong,Guiyuan Li +16 more
TL;DR: It is suggested that LPLUNC1 can inhibit inflammation and NPC growth by downregulating the Stat3 pathway.
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Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth.
Hailin Tang,Xiaoping Liu,Zeyou Wang,Xiaoling She,Xi Zeng,Xi Zeng,Min Deng,Min Deng,Qianjin Liao,Qianjin Liao,Xiaofang Guo,Rong Wang,Xiaoling Li,Fang Zeng,Minghua Wu,Guiyuan Li +15 more
TL;DR: By regulating LRRC4, hsa-miR-381 increased the in vitro and in vivo proliferation of glioma cells, and this action was associated with decreased inhibition of MEK/ERK and AKT signaling.
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An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma
Zhaohui Luo,Liyang Zhang,Zheng Li,Xiayu Li,Gang Li,Haibo Yu,Chen Jiang,Yafei Dai,Xiaofang Guo,Juanjuan Xiang,Guiyuan Li +10 more
TL;DR: It is concluded that miRNAs might play important regulatory roles through the target genes and transcription factors in the stepwise development of NPC and proposed an integrative strategy for identifying the miRNA-mRNA regulatory modules and TF-miRNA regulatory networks.