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Guiyuan Li

Researcher at Central South University

Publications -  345
Citations -  14981

Guiyuan Li is an academic researcher from Central South University. The author has contributed to research in topics: Nasopharyngeal carcinoma & Cancer. The author has an hindex of 58, co-authored 329 publications receiving 11272 citations. Previous affiliations of Guiyuan Li include Chinese Ministry of Education & Cancer Research Institute.

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Analysis of status and countermeasures of cancer incidence and mortality in China.

TL;DR: This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China.
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MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression

TL;DR: The data strongly support a central role for miR-125b in conferring Taxol resistance through the suppression of Bak1 expression, which has important implications in the development of targeted therapeutics for overcoming taxol resistance in a number of different tumor histologies.
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Neoantigen vaccine: an emerging tumor immunotherapy

TL;DR: Tumor vaccines targeting neoantigens mainly include nucleic acid, dendritic cell (DC)-based, tumor cell, and synthetic long peptide (SLP) vaccines, which might achieve better therapeutic effects in the future.
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Circular RNAs in human cancer

TL;DR: The role of circRNAs as molecular markers or potential targets will provide promising application perspectives, such as early tumor diagnosis, therapeutic evaluation, prognosis prediction, and even gene therapy for tumors.
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Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT

TL;DR: Exosome-mediated transfer of select microRNAs from BMSCs to epithelial cancer cells activates STAT3 signaling and increases the expression of mesenchymal related molecules, which may be promising noninvasive biomarkers for cancer progression.