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Bo Xiang
Researcher at Chinese Ministry of Education
Publications - 147
Citations - 6625
Bo Xiang is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Nasopharyngeal carcinoma & Cancer. The author has an hindex of 36, co-authored 116 publications receiving 4248 citations. Previous affiliations of Bo Xiang include Central South University & Cancer Research Institute.
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Journal ArticleDOI
Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape.
Xianjie Jiang,Xianjie Jiang,Jie Wang,Xiangying Deng,Fang Xiong,Junshang Ge,Junshang Ge,Bo Xiang,Bo Xiang,Xu Wu,Xu Wu,Jian Ma,Jian Ma,Ming Zhou,Ming Zhou,Xiaoling Li,Xiaoling Li,Yong Li,Yong Li,Guiyuan Li,Guiyuan Li,Wei Xiong,Wei Xiong,Can Guo,Can Guo,Zhaoyang Zeng,Zhaoyang Zeng +26 more
TL;DR: Overall, the evidence accumulated to date suggests that induction of PD-L1 by inflammatory factors in the tumor microenvironment may be one of the most important factors affecting the therapeutic efficiency of PD -L1/PD-1 blocking.
Journal ArticleDOI
Circular RNAs in human cancer
Yumin Wang,Yongzhen Mo,Zhaojian Gong,Xiang Yang,Mo Yang,Shanshan Zhang,Fang Xiong,Bo Xiang,Ming Zhou,Qianjin Liao,Wenling Zhang,Xiayu Li,Xiaoling Li,Yong Li,Yong Li,Guiyuan Li,Zhaoyang Zeng,Wei Xiong +17 more
TL;DR: The role of circRNAs as molecular markers or potential targets will provide promising application perspectives, such as early tumor diagnosis, therapeutic evaluation, prognosis prediction, and even gene therapy for tumors.
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Role of metabolism in cancer cell radioresistance and radiosensitization methods.
Le Tang,Le Tang,Fang Wei,Fang Wei,Yingfen Wu,Yi He,Yi He,Lei Shi,Fang Xiong,Zhaojian Gong,Can Guo,Xiayu Li,Xiayu Li,Hao Deng,Ke Cao,Ming Zhou,Ming Zhou,Bo Xiang,Bo Xiang,Xiaoling Li,Xiaoling Li,Yong Li,Yong Li,Guiyuan Li,Guiyuan Li,Wei Xiong,Wei Xiong,Zhaoyang Zeng,Zhaoyang Zeng +28 more
TL;DR: The aim of this review was to provide a theoretical basis and relevant references, which may lead to the improvement of the sensitivity of radiotherapy and prolong the survival of cancer patients.
Journal ArticleDOI
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Hao Bo,Zhaojian Gong,Wenling Zhang,Xiayu Li,Yong Zeng,Qianjin Liao,Pan Chen,Lei Shi,Yu Lian,Yizhou Jing,Ke Tang,Zheng Li,Yanhong Zhou,Ming Zhou,Bo Xiang,Xiaoling Li,Jianbo Yang,Jianbo Yang,Wei Xiong,Guiyuan Li,Zhaoyang Zeng +20 more
TL;DR: Proteomic and bioinformatics analyses suggested that AFAP1-AS1 affected the expression of several small GTPase family members and molecules in the actin cytokeratin signaling pathway and promoted cancer cell metastasis via regulation of actin filament integrity.
Journal ArticleDOI
The role of microenvironment in tumor angiogenesis
Xianjie Jiang,Xianjie Jiang,Jie Wang,Xiangying Deng,Fang Xiong,Shanshan Zhang,Zhaojian Gong,Xiayu Li,Ke Cao,Hao Deng,Yi He,Qianjin Liao,Bo Xiang,Bo Xiang,Ming Zhou,Ming Zhou,Can Guo,Zhaoyang Zeng,Zhaoyang Zeng,Guiyuan Li,Guiyuan Li,Xiaoling Li,Xiaoling Li,Wei Xiong,Wei Xiong +24 more
TL;DR: The regulatory role of the microenvironment in tumor angiogenesis is discussed and high expression of angiogenic factors and inflammatory cytokines in the tumor microenvironment, as well as hypoxia, are presumed to be the reasons for poor therapeutic efficacy of current anti-angiogenic drugs.