Xiaoning Wang

TL;DR: It is suggested that digitoflavone is a novel Nrf2 pathway activator, and protects against oxidative stress-induced cell injury, and reaffirm its potential role as a chemopreventive agent in colorectal carcinogenesis.

TL;DR: This study examined the question whether or not luteolin can inhibit proliferation of pancreatic carcinoma cells, via programmed cell death (apoptosis), by inhibiting HUVEC proliferation and vessel growth and downregulated the concentration of VEGF in the conditioned medium.

TL;DR: Accumulation of evidences suggested that AC591 can prevent oxaliplatin-induced neuropathy without reducing its antitumor activity, and may be a promising adjuvant to alleviate sensory symptoms in clinical practice.

TL;DR: It is found that Weikang Keli could induce patterns of autophagy in SGC-7901 cells, including intracellular vacuole formation, microtubule-associated protein 1 light chain 3 (LC3) conversion, and Hoechst 33258 staining and Western blot analysis of apoptosis-related proteins showed that WK induced SGC -7901 cell death was not through apoptosis.

TL;DR: Findings strongly suggested that these scopoletin derivatives might be structurally novel angiogenesis inhibitors.