Xiaoying Yang

TL;DR: The data suggest that elevating consumption of β-glucan-rich foods is an easily implementable nutritional strategy to alleviate detrimental features of gut-brain dysregulation and prevent neurodegenerative diseases associated with Westernized dietary patterns.

TL;DR: In this article, a mouse model of long-term (15 weeks) dietary fiber deficiency was used to mimic a sustained low fiber intake in humans, and it was found that FD mice showed impaired cognition, including deficits in object location memory, temporal order memory, and the ability to perform daily living activities.

TL;DR: In this article, the effects of Lentinula edodes derived β-glucan against high-fat (HF) diet intake can cause neuroinflammation and cognitive decline through the gut-brain axis.

TL;DR: It is found that acute curdlan supplementation prevented the gut microbial composition shift induced by HF diet and mitigated microgliosis, neuroinflammation, and synaptic impairments induced by a HF diet, and curdLAN—as a food additive and prebiotic—can prevent cognitive deficits induced byHF diet via the colon-brain axis.

TL;DR: The expression, biological function and associated mechanisms of IL‐34 in HBV‐related HCC cells were investigated and it was found that the activity in these cells is related to HBV infection and hepatocellular carcinoma.