Renxian Tang

TL;DR: The data suggest that elevating consumption of β-glucan-rich foods is an easily implementable nutritional strategy to alleviate detrimental features of gut-brain dysregulation and prevent neurodegenerative diseases associated with Westernized dietary patterns.

TL;DR: The findings suggest that the mechanism of astaxanthin in preventing depression in diabetic mice involves the inhibition of inflammation/inflammation inhibition, thereby protecting neurons in hippocampus, amygdala and hypothalamus against hyperglycemic damage.

TL;DR: It is elucidated that miR‐409‐3p and miR-1896, as co‐upregulated microRNAs in activated astrocytes and in EAE mice, targeted suppressor of cytokine signaling proteins 3 (SOCS3), which may be a therapeutic target for treating MS and neuroinflammation.

TL;DR: In this article, a mouse model of long-term (15 weeks) dietary fiber deficiency was used to mimic a sustained low fiber intake in humans, and it was found that FD mice showed impaired cognition, including deficits in object location memory, temporal order memory, and the ability to perform daily living activities.

TL;DR: The results of the present study indicated for the first time that the activation of TGF-β/Smad signaling pathway might contribute to the synthesis of collagen type I which leads to liver fibrosis caused by C. sinensis.