Xin Guan

TL;DR: The polymer encapsulation of the monoclonal antibody rituximab and the ligand-mediated targeting of metastases in the central nervous system significantly improve antitumour efficacy in mouse models of metastatic non-Hodgkin lymphoma.

TL;DR: It is reported that functional human erythrocytes can be efficiently produced from cord blood (CB) CD34+ cells using a bottle turning device culture system and suggested that the ex vivo‐generated ery Throcytes could be an alternative blood source for traditional transfusion products in the clinic.

TL;DR: An optimal small-molecule/cytokine combination for the enhancement of HSC expansion via inhibition of differentiation is developed and indicates promising application for preparation of both the HSCs and the mature, functional hematopoietic cells for clinical transplantation.

TL;DR: An approach for the generation of cord blood-derived EPCs/ECs on a large scale was developed, characterized them phenotypically, and demonstrated their in-vivo functional capacity.

TL;DR: The development of an efficient two‐stage culture system that is free of stroma, animal components, and genetic manipulations for the production of functional megakaryocytes from hematopoietic stem cells is reported, suggesting that large‐scale induction of functionalmegakaryocytic cells is applicable for treating thrombocytopenic blood diseases in the clinic.