Yu Zhang

TL;DR: It is reported that functional human erythrocytes can be efficiently produced from cord blood (CB) CD34+ cells using a bottle turning device culture system and suggested that the ex vivo‐generated ery Throcytes could be an alternative blood source for traditional transfusion products in the clinic.

TL;DR: An optimal small-molecule/cytokine combination for the enhancement of HSC expansion via inhibition of differentiation is developed and indicates promising application for preparation of both the HSCs and the mature, functional hematopoietic cells for clinical transplantation.

TL;DR: An approach for the generation of cord blood-derived EPCs/ECs on a large scale was developed, characterized them phenotypically, and demonstrated their in-vivo functional capacity.

TL;DR: The development of an efficient two‐stage culture system that is free of stroma, animal components, and genetic manipulations for the production of functional megakaryocytes from hematopoietic stem cells is reported, suggesting that large‐scale induction of functionalmegakaryocytic cells is applicable for treating thrombocytopenic blood diseases in the clinic.

TL;DR: The expansion of nonhuman primate bone marrow-derived CD34+ cells is investigated using the Sall4B lentiviral overexpression approach to provide a new perspective on mechanisms of rapid stem cell proliferation.