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Xindi Shan
Researcher at Ocean University of China
Publications - 18
Citations - 1042
Xindi Shan is an academic researcher from Ocean University of China. The author has contributed to research in topics: Fucoidan & Mucin. The author has an hindex of 11, co-authored 16 publications receiving 676 citations. Previous affiliations of Xindi Shan include Oklahoma Medical Research Foundation.
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Journal ArticleDOI
Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae
TL;DR: Modulations of gut microbiota by different fucoidans were studied and it was found that at the expense of opportunistic pathogenic bacteria such as Peptococcus, the abundance of beneficial bacteria was significantly increased in response to fucoidan treatment.
Journal ArticleDOI
Spongy bilayer dressing composed of chitosan-Ag nanoparticles and chitosan-Bletilla striata polysaccharide for wound healing applications.
Ding Lang,Xindi Shan,Xiaoliang Zhao,Hualian Zha,Xiaoyu Chen,Jianjun Wang,Chao Cai,Xiaojiang Wang,Guoyun Li,Jiejie Hao,Guangli Yu +10 more
TL;DR: The in vivo studies indicated that both CSGB and bilayer wound dressing significantly accelerated the healing rate of cutaneous wounds in mice, and the bilayer exhibited better mature epidermization with less inflammatory cells on Day 7, therefore, this novel bilayer composite has great potential in wound dressing applications.
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Carrageenan-induced colitis is associated with decreased population of anti-inflammatory bacterium, Akkermansia muciniphila, in the gut microbiota of C57BL/6J mice.
TL;DR: The results corroborate previous studies demonstrating harmful gastrointestinal effect of carrageenan and shed new light into the mechanism by which carrageENan induces colitis in experimental animals.
Journal ArticleDOI
In vitro and in vivo hypoglycemic effects of brown algal fucoidans
Xindi Shan,Xin Liu,Jiejie Hao,Chao Cai,Fei Fan,Yunlou Dun,Xiaoliang Zhao,Xiaoxiao Liu,Chunxia Li,Guangli Yu +9 more
TL;DR: In vitro and in vivo studies demonstrated that FvF could be a promising α-glucosidase inhibitor for the treatment of type 2 diabetes mellitus.
Journal ArticleDOI
Proximal colon–derived O-glycosylated mucus encapsulates and modulates the microbiota
Kirk Bergstrom,Kirk Bergstrom,Xindi Shan,David Casero,Albert Batushansky,Venu Lagishetty,Jonathan P. Jacobs,Christopher M. Hoover,Yuji Kondo,Bojing Shao,Liang Gao,Wesley F. Zandberg,Benjamin Noyovitz,J. Michael McDaniel,Deanna L. Gibson,Sepideh Pakpour,Negin Kazemian,Samuel McGee,Courtney W. Houchen,Chinthalapally V. Rao,Timothy M. Griffin,Timothy M. Griffin,Justin L. Sonnenburg,Rodger P. McEver,Rodger P. McEver,Jonathan Braun,Lijun Xia,Lijun Xia +27 more
TL;DR: In mice, it is found that colon mucus consists of two distinct O-glycosylated entities of Muc2: a major form produced by the proximal colon, which encapsulates the fecal material including the microbiota, and a minor form derived from the distal Colon, which adheres to the major form.