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Xinyi Tang
Researcher at Mayo Clinic
Publications - 4
Citations - 92
Xinyi Tang is an academic researcher from Mayo Clinic. The author has contributed to research in topics: T cell & Follicular lymphoma. The author has an hindex of 2, co-authored 4 publications receiving 31 citations.
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Journal ArticleDOI
TIGIT expression is associated with T-cell suppression and exhaustion and predicts clinical outcome and anti-PD-1 response in follicular lymphoma
Zhi Zhang Yang,Hyo Jin Kim,Hongyan Wu,Shahrzad Jalali,Xinyi Tang,Jordan E. Krull,Wei Ding,Anne J. Novak,Stephen M. Ansell +8 more
TL;DR: Inhibition of TIGIT signaling may be an additional mechanism to prevent T-cell suppression and exhaustion in B-cell lymphoma.
Journal ArticleDOI
Increased glutathione utilization augments tumor cell proliferation in Waldenstrom Macroglobulinemia.
Shahrzad Jalali,Jie Shi,Alex Buko,Nagib Ahsan,Jonas Paludo,MaKayla R Serres,Linda Wellik,Jithma P. Abeykoon,Hyo Jin Kim,Xinyi Tang,Zhi Zhang Yang,Anne J. Novak,Thomas E. Witzig,Stephen M. Ansell +13 more
TL;DR: The data highlight a central role for glutathione metabolism in WM pathobiology and indicate that intervening with the metabolic processes could be a potential therapy for WM patients.
Journal ArticleDOI
High-dimensional and single-cell transcriptome analysis of the tumor microenvironment in angioimmunoblastic T cell lymphoma (AITL).
Joshua C. Pritchett,Zhi-Zhang Yang,Hyo Jin Kim,Jose C. Villasboas,Xinyi Tang,Shahrzad Jalali,James R. Cerhan,Andrew L. Feldman,Stephen M. Ansell +8 more
TL;DR: In this paper, the authors used mass cytometry and single-cell transcriptome analysis to identify several expanded populations within the AITL tumor microenvironment (TME) and found that B cells within the TME feature decreased expression of key markers including CD73 and CXCR5.
Journal ArticleDOI
Expression of KLRG1 and CD127 defines distinct CD8+ subsets that differentially impact patient outcome in follicular lymphoma.
Hongyan Wu,Xinyi Tang,Hyo Jin Kim,Shahrzad Jalali,Joshua C. Pritchett,Jose C. Villasboas,Anne J. Novak,Zhi-Zhang Yang,Stephen M. Ansell +8 more
TL;DR: In this paper, the effector subsets exhibited increased capacity to produce cytokines/granules when compared with memory subsets, while their proliferative capacity and viability were substantially inferior.