H
Hongyan Wu
Researcher at China Three Gorges University
Publications - 5
Citations - 156
Hongyan Wu is an academic researcher from China Three Gorges University. The author has contributed to research in topics: Follicular lymphoma & CD28. The author has an hindex of 3, co-authored 5 publications receiving 77 citations.
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Journal ArticleDOI
TIGIT expression is associated with T-cell suppression and exhaustion and predicts clinical outcome and anti-PD-1 response in follicular lymphoma
Zhi Zhang Yang,Hyo Jin Kim,Hongyan Wu,Shahrzad Jalali,Xinyi Tang,Jordan E. Krull,Wei Ding,Anne J. Novak,Stephen M. Ansell +8 more
TL;DR: Inhibition of TIGIT signaling may be an additional mechanism to prevent T-cell suppression and exhaustion in B-cell lymphoma.
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Mass Cytometry Analysis Reveals that Specific Intratumoral CD4+ T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma
Zhi Zhang Yang,Hyo Jin Kim,Jose C. Villasboas,Tammy Price-Troska,Shahrzad Jalali,Hongyan Wu,Rebecca A. Luchtel,Mei Yin C. Polley,Anne J. Novak,Stephen M. Ansell +9 more
TL;DR: These mass cytometry results identified CD4+ memory T cell populations that are poorly functional due to loss of co-stimulatory receptor expression and are associated with an inferior survival in FL.
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SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphoma.
Ya Ping Chen,Hyo Jin Kim,Hongyan Wu,Tammy Price-Troska,Jose C. Villasboas,Shahrzad Jalali,Andrew L. Feldman,Anne J. Novak,Zhi Zhang Yang,Stephen M. Ansell +9 more
TL;DR: The results show that SIRPα expression delineates unique subsets of intratumoral Mo/MΦs with differing prognostic importance, and Clinically, increased numbers of CD14+SirPαhi cells were associated with an inferior survival in FL, and increased number of the CD14−SIRP αlow subset appeared to correlate with a better survival.
Journal ArticleDOI
Expression of KLRG1 and CD127 defines distinct CD8+ subsets that differentially impact patient outcome in follicular lymphoma.
Hongyan Wu,Xinyi Tang,Hyo Jin Kim,Shahrzad Jalali,Joshua C. Pritchett,Jose C. Villasboas,Anne J. Novak,Zhi-Zhang Yang,Stephen M. Ansell +8 more
TL;DR: In this paper, the effector subsets exhibited increased capacity to produce cytokines/granules when compared with memory subsets, while their proliferative capacity and viability were substantially inferior.
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Tigit Expression Defines a Subset of Activated Treg Cells with Prognostic Relevance in Follicular Lymphoma
TL;DR: A role of TIGIT is revealed in defining Treg cell subsets with different immune function and TIGit expression may be useful in predicting patient outcome in FL.