Xiong Cai

TL;DR: Spirobisnaphthalenes have a unique structural feature involving two or three oxygen atoms acting as bridges connecting two original naphthalene subunits, and exhibit significant antifungal, antibacterial and cytotoxic properties.

TL;DR: The administration of an intradermal injection of only 200 µg bovine CII emulsified in IFA at the base of the tail leads to the successful development of a CIA rat model that could be specifically used to study the pathophysiology of human rheumatoid arthritis as well as to test and develop anti-arthritic agents for humans.

TL;DR: The data demonstrate that AT-I stimulates intestinal epithelial cell migration and proliferation via the polyamine-mediated Ca2+ signaling pathway, and may have the potential to be further developed as a promising therapeutic agent to treat diseases associated with gastrointestinal mucosal injury, such as inflammatory bowel disease and peptic ulcer.

TL;DR: In antimalarial, antimicrobial, anti-inflammatory, PPAR and cytotoxic assays, some compounds have demonstrated moderate inhibitory potentials.

TL;DR: KHS demonstrates potential anti-arthritic effects via inhibiting pivotal mediators of inflammation and cartilage destruction through inhibition of MMP-3 and TIMP-1, and strongly supports identification and isolation of active fractions of KHS which would be a potential candidate for further investigation as a new anti-ithritic botanical drug.