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Xuexue Liu

Researcher at Civil Aviation Authority of Singapore

Publications -  27
Citations -  363

Xuexue Liu is an academic researcher from Civil Aviation Authority of Singapore. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 8, co-authored 15 publications receiving 205 citations.

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Exome sequencing reveals genetic differentiation due to high-altitude adaptation in the Tibetan cashmere goat ( Capra hircus )

TL;DR: The study provides insights concerning the population variation in six different cashmere goat populations in China and reveals variants in cardiovascular system-related genes that may explain the observed phenotypic adaptation of the Tibetan cashmere Goat.
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EPAS1 gain-of-function mutation contributes to high altitude adaptation in Tibetan horses

TL;DR: It is demonstrated that missense mutations in the EPAS1 gene provided key evolutionary molecular adaptation to Tibetan horses living in high-altitude hypoxic environments, revealing possible targets for genomic selection programs aimed at increasing hypoxia tolerance in livestock and providing a textbook example of evolutionary convergence across independent mammal lineages.
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Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array.

TL;DR: A Chinese indigenous sheep genomic CNV map is constructed based on the Illumina Ovine SNP 600 K BeadChip array, providing an important addition to published sheep CNVs, which will be helpful for future investigations of the genomic structural variations underlying traits of interest in sheep.
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Population Variation Reveals Independent Selection toward Small Body Size in Chinese Debao Pony

TL;DR: Comparison of individual horses from the Debao population with other two Chinese horse populations using single nucleotide polymorphisms identified with the Equine SNP 65 Bead Chip demonstrated that TBX3 was selected independently in theDebao pony, suggesting that there were multiple origins of small stature in the horse.
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Genome-Wide Runs of Homozygosity, Effective Population Size, and Detection of Positive Selection Signatures in Six Chinese Goat Breeds.

TL;DR: This study provides a new insight into the ROHs patterns for maintenance of within breed diversity and suggests a role of positive selection for genetic variation influencing fecundity in Chinese goat.