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Xuexue Liu
Researcher at Civil Aviation Authority of Singapore
Publications - 27
Citations - 363
Xuexue Liu is an academic researcher from Civil Aviation Authority of Singapore. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 8, co-authored 15 publications receiving 205 citations.
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Journal ArticleDOI
Exome sequencing reveals genetic differentiation due to high-altitude adaptation in the Tibetan cashmere goat ( Capra hircus )
Shen Song,Shen Song,Na Yao,Min Yang,Xuexue Liu,Kunzhe Dong,Qianjun Zhao,Yabin Pu,Xiaohong He,Weijun Guan,Ning Yang,Yuehui Ma,Lin Jiang +12 more
TL;DR: The study provides insights concerning the population variation in six different cashmere goat populations in China and reveals variants in cardiovascular system-related genes that may explain the observed phenotypic adaptation of the Tibetan cashmere Goat.
Journal ArticleDOI
EPAS1 gain-of-function mutation contributes to high altitude adaptation in Tibetan horses
Xuexue Liu,Zhang Yanli,Yefang Li,Jianfei Pan,Dandan Wang,Weihuang Chen,Zhuqing Zheng,Xiaohong He,Qianjun Zhao,Yabin Pu,Weijun Guan,Jian-Lin Han,Ludovic Orlando,Yuehui Ma,Lin Jiang +14 more
TL;DR: It is demonstrated that missense mutations in the EPAS1 gene provided key evolutionary molecular adaptation to Tibetan horses living in high-altitude hypoxic environments, revealing possible targets for genomic selection programs aimed at increasing hypoxia tolerance in livestock and providing a textbook example of evolutionary convergence across independent mammal lineages.
Journal ArticleDOI
Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array.
Qing Ma,Xuexue Liu,Jianfei Pan,Ma Lina,Yuehui Ma,Xiaohong He,Qianjun Zhao,Yabin Pu,Li Yingkang,Lin Jiang +9 more
TL;DR: A Chinese indigenous sheep genomic CNV map is constructed based on the Illumina Ovine SNP 600 K BeadChip array, providing an important addition to published sheep CNVs, which will be helpful for future investigations of the genomic structural variations underlying traits of interest in sheep.
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Population Variation Reveals Independent Selection toward Small Body Size in Chinese Debao Pony
Adiljan Kader,Yan Li,Kunzhe Dong,David M. Irwin,Qianjun Zhao,Xiaohong He,Jianfeng Liu,Yabin Pu,Neena Amatya Gorkhali,Xuexue Liu,Lin Jiang,Xiangchen Li,Weijun Guan,Ya-Ping Zhang,Dong-Dong Wu,Yuehui Ma +15 more
TL;DR: Comparison of individual horses from the Debao population with other two Chinese horse populations using single nucleotide polymorphisms identified with the Equine SNP 65 Bead Chip demonstrated that TBX3 was selected independently in theDebao pony, suggesting that there were multiple origins of small stature in the horse.
Journal ArticleDOI
Genome-Wide Runs of Homozygosity, Effective Population Size, and Detection of Positive Selection Signatures in Six Chinese Goat Breeds.
Rabiul Islam,Yefang Li,Xuexue Liu,Haile Berihulay,Adam Abied,Gebremedhin Gebreselassie,Qing Ma,Yuehui Ma +7 more
TL;DR: This study provides a new insight into the ROHs patterns for maintenance of within breed diversity and suggests a role of positive selection for genetic variation influencing fecundity in Chinese goat.