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Yan Li
Researcher at Yunnan University
Publications - 43
Citations - 1535
Yan Li is an academic researcher from Yunnan University. The author has contributed to research in topics: Population & Gene. The author has an hindex of 19, co-authored 43 publications receiving 1210 citations. Previous affiliations of Yan Li include Laboratory of Molecular Biology & Kunming Institute of Zoology.
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Journal ArticleDOI
Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens
Ming-Shan Wang,Yan Li,Min-Sheng Peng,Li Zhong,Zongji Wang,Qiye Li,Xiao-Long Tu,Yang Dong,Chun-Ling Zhu,Lu Wang,Min-Min Yang,Shi-Fang Wu,Yong-Wang Miao,Jian-Ping Liu,David M. Irwin,Wen Wang,Dong-Dong Wu,Ya-Ping Zhang +17 more
TL;DR: A de novo genome of a Tibetan chicken is assembled and whole genomes of 32 additional chickens, including Tibetan chickens, village chickens, game fowl, and Red Junglefowl are resequenced, and it is found that the Tibetan chickens could broadly be placed into two groups.
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Pervasive introgression facilitated domestication and adaptation in the Bos species complex.
Dong-Dong Wu,Dong-Dong Wu,Xiangdong Ding,Sheng Wang,Jan M. Wójcik,Yi Zhang,Małgorzata Tokarska,Yan Li,Ming-Shan Wang,Ming-Shan Wang,Omar Faruque,Rasmus Nielsen,Qin Zhang,Qin Zhang,Ya-Ping Zhang,Ya-Ping Zhang +15 more
TL;DR: It is suggested that the Bos genus evolves as a complex of genetically interconnected species with shared evolutionary trajectories, and that the threatened gayal is an independent species or subspecies.
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Quantification of extrapulmonary translocation of intratracheal-instilled particles in vivo in rats: effect of lipopolysaccharide.
TL;DR: Only a small fraction of intratracheal-instilled ultrafine particles can pass rapidly into systemic circulation, but this translocation is markedly increased following LPS pretreatment, and pulmonary inflammation seems to play a major role in enhancing the extrapulmonary translocation of particles.
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Population variation revealed high altitude adaptation of Tibetan Mastiffs
Yan Li,Dong-Dong Wu,Dong-Dong Wu,Adam R. Boyko,Guo-Dong Wang,Guo-Dong Wang,Shi-Fang Wu,David M. Irwin,David M. Irwin,Ya-Ping Zhang,Ya-Ping Zhang,Ya-Ping Zhang +11 more
TL;DR: This study genotyped genome-wide single-nucleotide polymorphisms (SNPs) from 32 TMs and compared them with SNPs from 20 Chinese native dogs and 14 gray wolves to identify 16 genes with signals of positive selection in the TM and potential mechanisms for adaptation to hypoxia.
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Genetic convergence in the adaptation of dogs and humans to the high altitude environment of the Tibetan plateau
Guo-Dong Wang,Ruo-xi Fan,Weiwei Zhai,Fei Liu,Lu Wang,Li Zhong,Hong Wu,He-Chuan Yang,Shi-Fang Wu,Chun-Ling Zhu,Yan Li,Yun Gao,Ri-Li Ge,Chung-I Wu,Ya-Ping Zhang +14 more
TL;DR: It is found that the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive strategies as the Tibetan people.