Polysaccharides/Halloysite nanotubes for smart bionanocomposite materials

A review on magnetic sensors for monitoring of hazardous pollutants in water resources

A review on the preparation of chitosan oligosaccharides and application to human health, animal husbandry and agricultural production.

Graphene, a wonder material, has made far-reaching developments in many different fields such as materials science, electronics, condensed physics, quantum physics, energy systems, etc. Since its discovery in 2004, extensive studies have been done for understanding its physical and chemical properties. Owing to its unique characteristics, it has rapidly became a potential candidate for nano-bio researchers to explore its usage in biomedical applications. In the last decade, remarkable efforts have been devoted to investigating the biomedical utilization of graphene and graphene-based materials, especially in smart drug and gene delivery as well as cancer therapy. Inspired by a great number of successful graphene-based materials integrations into the biomedical area, here we summarize the most recent developments made about graphene applications in biomedicine. In this paper, we review the up-to-date advances of graphene-based materials in drug delivery applications, specifically targeted drug/ gene delivery, delivery of antitumor drugs, controlled and stimuli-responsive drug release, photodynamic therapy applications and optical imaging and theranostics, as well as investigating the future trends and succeeding challenges in this topic to provide an outlook for future researches.

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Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?

The arena of biomedical science has long been in quest of innovative mediums for diagnostic and therapeutic applications. The latest being the use of nanomaterials for such applications, thereby giving rise to the branch of nanomedicine. Halloysite nanotubes (HNTs) are naturally occurring tubular clay nanomaterials, made of aluminosilicate kaolin sheets rolled several times. The aluminol and siloxane groups on the surface of HNT facilitate the formation of hydrogen bonding with the biomaterials onto its surface. These properties render HNT pivotal in diverse range of applications, such as in environmental sciences, waste-water treatment, dye removal, nanoelectronics and fabrication of nanocomposites, catalytic studies, as glass coatings or anticorrosive coatings, in cosmetics, as flame retardants, stimuli response, and forensic sciences. The specific properties of HNT also lead to numerous applications in biomedicine and nanomedicine, namely drug delivery, gene delivery, tissue engineering, cancer and stem cells isolation, and bioimaging. In this review, recent developments in the use of HNT for various nanomedicinal applications have been discussed.

https://journals.sagepub.com/doi/pdf/10.1177/1849543519863625

Halloysite nanotubes as a nature’s boon for biomedical applications:

Folic acid-conjugated chitosan oligosaccharide-magnetic halloysite nanotubes as a delivery system for camptothecin

QbD approach by computer aided design and response surface methodology for molecularly imprinted polymer based on magnetic halloysite nanotubes for extraction of norfloxacin from real samples

Preparation of novel molecularly imprinted magnetic graphene oxide and their application for quercetin determination.

In this study, we propose the first use of polyethylene glycol (PEG) as a carbon precursor via a spontaneous exothermic reaction involving phosphorus pentoxide (P2O5) to synthesize fluorescent carbon nanoparticles (FCNPs). The unique FCNPs, which emit bluish violet light under UV light, have a diameter of less than 10 nm and a high quantum yield of 18.4%. Moreover, the FCNPs without further treatments show excellent thermosensitivity, excitation-dependent multicolor emission, high solubility in water, and superior photostability. This facile, economical and convenient route is expected to inspire more research into the origin and applications of FCNPs, as well as delivering FCNP-based materials.

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Yamina Ait Mehdi

Papers

Folic acid-conjugated chitosan oligosaccharide-magnetic halloysite nanotubes as a delivery system for camptothecin

QbD approach by computer aided design and response surface methodology for molecularly imprinted polymer based on magnetic halloysite nanotubes for extraction of norfloxacin from real samples

Preparation of novel molecularly imprinted magnetic graphene oxide and their application for quercetin determination.

One-step spontaneous synthesis of fluorescent carbon nanoparticles with thermosensitivity from polyethylene glycol

Preparation of novel molecularly imprinted magnetic graphene oxide and their application for quercetin determination