Y
Yan Chen
Researcher at Curtin University
Publications - 5
Citations - 785
Yan Chen is an academic researcher from Curtin University. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 1, co-authored 2 publications receiving 657 citations.
Papers
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Journal ArticleDOI
Modern methods for delivery of drugs across the blood-brain barrier.
Yan Chen,Lihong Liu +1 more
TL;DR: This review will discuss the barrier issue from a biological and pathological perspective to provide a better insight to the challenges and opportunities associated with the BBB.
Journal ArticleDOI
Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer
Hanshen Yang,Xiaozhen Zhang,Mengyi Lao,Kang Sun,Lihong He,Jian Hui Xu,Yi Duan,Yan Chen,H. Ying,Muchun Li,Cheng-Xiang Guo,Qingsong Lu,Sicheng Wang,Wei Su,Tingbo Liang,Xueli Bai +15 more
TL;DR: Zhang et al. as discussed by the authors found that ubiquitin-specific protease 8 (USP8) deubiquitinates PD-L1 and upregulated its expression by inhibiting the ubiquitination-regulated proteasome degradation pathway in pancreatic cancer.
Journal ArticleDOI
Targeting prolyl isomerase Pin1 as a promising strategy to overcome resistance to cancer therapies.
TL;DR: Wang et al. as mentioned in this paper summarized the functions and mechanisms of prolyl isomerase Pin1 in therapeutic resistance of multifarious cancers, such as breast, liver, and pancreatic carcinomas.
Journal ArticleDOI
Nanoformulated antimicrobial agents for central nervous system infections
Book ChapterDOI
Surveillance and response systems driving malaria elimination in the mountain areas of Hainan Province.
Yuchun Li,Shan Qing Wang,Xi-min Hu,Yingjuan Huang,Renqiang Chen,M. Lin,Rongshen Ye,D. Zhan,Shaoli Huang,Ji Zhen,Xi Wen,Guoyi Wang,Yong Liu,Haishan Li,Z. Zheng,Jian Wang,Wen Zeng,Feng Meng,X. Huang,Guang-ze Wang,Bing Yang,Yan Chen +21 more
TL;DR: Wang et al. as discussed by the authors summarized the malaria monitoring in forest goers and the response of forest-goers to malaria control and elimination in Hainan Province, distilling specific malaria-control and elimination measures via case studies.