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Yan-Der Hsuuw
Researcher at National Pingtung University of Science and Technology
Publications - 20
Citations - 547
Yan-Der Hsuuw is an academic researcher from National Pingtung University of Science and Technology. The author has contributed to research in topics: Apoptosis & Embryonic stem cell. The author has an hindex of 11, co-authored 20 publications receiving 482 citations. Previous affiliations of Yan-Der Hsuuw include Fooyin University & Memorial Hospital of South Bend.
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Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts.
TL;DR: The hypothesis that curcumin inhibits MG‐induced apoptosis in mouse ESC‐B5 cells and blastocysts by blocking ROS formation and subsequent apoptotic biochemical events is supported.
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Protective effects of resveratrol on ethanol-induced apoptosis in embryonic stem cells and disruption of embryonic development in mouse blastocysts.
TL;DR: It is shown that 0.3-1.0% (w/v) ethanol induces apoptosis in mouse blastocysts and that resveratrol, a grape-derived phytoalexin with known antioxidant and anti-inflammatory properties, prevents ethanol-induced apoptosis and inhibition of cell proliferation.
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Retinoic acid decreases the viability of mouse blastocysts in vitro
TL;DR: This is the first evidence that retinoic acid induces cell death (apoptosis) and inhibits cell proliferation in mouse blastocysts, which results in the retardation of early postimplantation blastocyst development and subsequent Blastocyst death.
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Androgenic and antiandrogenic effects and expression of androgen receptor in mouse embryonic stem cells
Chih-Yang Chang,Chih-Yang Chang,Yan-Der Hsuuw,Fu-Jen Huang,Chih-Rong Shyr,Shiuh-Young Chang,Chiung-Kuei Huang,Hong-Yo Kang,Ko-En Huang,Ko-En Huang +9 more
TL;DR: These findings provide the first evidence of the existence of AR in ESCs as the expression level of AR was increased in a stage-dependent but not a ligand-dependent manner during differentiation.
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Adverse effects of retinoic acid on embryo development and the selective expression of retinoic acid receptors in mouse blastocysts
Fu-Jen Huang,Yan-Der Hsuuw,Kou-Chung Lan,Hong-Yo Kang,Shiuh-Young Chang,Yu-Cheng Hsu,K E Huang +6 more
TL;DR: This is the first evidence to show the impacts of RA on mouse blastocyst in vitro and any carry-over effects in the uterus, and shows that there is some degree of selective induction of retinoic acid receptors when excess RA is administered to the blastocysts.