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Yan-Jun Kang
Researcher at Chinese Center for Disease Control and Prevention
Publications - 9
Citations - 881
Yan-Jun Kang is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: RNA virus & RNA. The author has an hindex of 5, co-authored 8 publications receiving 674 citations.
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Unprecedented genomic diversity of RNA viruses in arthropods reveals the ancestry of negative-sense RNA viruses
Ci-Xiu Li,Mang Shi,Jun-Hua Tian,Xian-Dan Lin,Yan-Jun Kang,Liangjun Chen,Xin-Cheng Qin,Jianguo Xu,Edward C. Holmes,Yong-Zhen Zhang +9 more
TL;DR: RNA sequencing of 70 arthropod species revealed that arthropods contain viruses that fall basal to major virus groups, including the vertebrate-specific arenaviruses, filoviruse, hantavirus, influenza viruses, lyssavirusing, and paramyxoviruses.
Journal ArticleDOI
A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors
Xin-Cheng Qin,Mang Shi,Mang Shi,Jun-Hua Tian,Xian-Dan Lin,Dong-Ya Gao,Jin-Rong He,Jian-bo Wang,Ci-Xiu Li,Yan-Jun Kang,Bin Yu,Dun-Jin Zhou,Jianguo Xu,Alexander Plyusnin,Alexander Plyusnin,Edward C. Holmes,Edward C. Holmes,Yong-Zhen Zhang +17 more
TL;DR: This work discovered a previously unidentified segmented RNA virus of ticks that, uniquely, contained two segments derived from an unsegmented flavivirus, as well as two highly divergent segments of unknown origin.
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Infection and pathogenesis of Huaiyangshan virus (a novel tick-borne bunyavirus) in laboratory rodents.
Xiao-Ping Chen,Mei-Li Cong,Ming-Hui Li,Yan-Jun Kang,Yan-Meng Feng,Alexander Plyusnin,Alexander Plyusnin,Jianguo Xu,Yong-Zhen Zhang +8 more
TL;DR: Huaiyangshan virus (HYSV) has been reported to cause haemorrhagic fever-like disease in mice and rats as discussed by the authors, but no animal experiments have been performed to study its pathogenesis.
Short Communication Infection and pathogenesis of Huaiyangshan virus (a novel tick-borne bunyavirus) in laboratory rodents
Xiao-Ping Chen,Mei-Li Cong,Ming-Hui Li,Yan-Jun Kang,Yan-Meng Feng,Alexander Plyusnin,Jianguo Xu,Yong-Zhen Zhang +7 more
TL;DR: It is demonstrated that HYSV can cause a lethal infection of both newborn mice and newborn rats with apparent pathological damage of the liver, and this animal model may help to understand the pathogenesis of the HysV infection in humans.
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Dynamics of hantavirus infections in humans and animals in Wuhan city, Hubei, China
Yan-Jun Kang,Dun-Jin Zhou,Jun-Hua Tian,Bin Yu,Wen-Ping Guo,Wen Wang,Ming-Hui Li,Tai-ping Wu,Jin-Song Peng,Alexander Plyusnin,Alexander Plyusnin,Yong-Zhen Zhang +11 more
TL;DR: Serological and genetic analyses showed that Hantaan virus (HTNV) and Seoul virus (SEOV) co-circulated in rodents in Wuhan, and Phylogenetic analysis of the hantavirus sequences revealed that a novel genetic lineage of HTNV is present in rodent in W Uhan.