Yan Li

TL;DR: It is demonstrated that ADSC‐derived exosomes can promote fibroblast proliferation and migration and optimize collagen deposition via the PI3K/Akt signaling pathway to further accelerate wound healing.

TL;DR: Host specific real-time PCR test of the neo-formed bone demonstrated that miR-26a optimized bone regeneration mainly due to simultaneously regulating endogenous angiogenesis-osteogenesis coupling, providing evidence that miRNA-based therapy can be a valuable tool to promote bone regeneration.

TL;DR: This study provides the first evidence that imbalanced mitochondrial dynamics induced by down-regulated Mfn2 contributes to the development of diabetic cardiomyopathy (DCM).

TL;DR: The role of miR-29b in anti-angiogenesis and anti-tumorigenesis is demonstrated is through targeting Akt3 and inducing VEGF and C-myc arrest in breast cancer cells, indicating that this single miRNA could be used as an efficient anti-cancer therapeutic agent to address a critical challenge in cancer therapy.

TL;DR: It is shown that resveratrol affects the growth of human breast cancer cell lines MCF7, MDA-MB-231, SK-BR-3, and Bcap-37 in a dose-dependent manner and thatMCF7 is the most sensitive among the four cell lines.