Yan-Yan Han

TL;DR: An efficient FeCl(3)-catalyzed stereoselective intramolecular tandem 1,5-hydride transfer/ring closure reaction was developed and allowed for the formation of structurally diverse spirooxindole tetrahydroquinolines in high yields with good to excellent levels of diastereoselectivity.

TL;DR: An efficient and stereoselective reaction between 3-isothiocyanato oxindoles and isatins/isatinimines has been developed to afford structurally diverse dispiro[oxazolidine-2-thione]bisoxindoles in excellent results under mild conditions.

TL;DR: A simple catalyst system assembled from an enantiomerically pure diamine ligand and Ni(OAc)(2) efficiently generates chiral metal enolates derived from 3-substituted oxindoles bearing an N-1 carbonyl group under mild reaction conditions.

TL;DR: This method provides access to spiro[oxazolidine-2-thione-oxindole] derivatives bearing two vicinal quaternary/tertiaries stereocenters in up to 95% yield, 98:2 dr, and 89% ee with a chiral bifunctional thiourea–tertiary amine organocatalyst based on DPEN scaffold.

TL;DR: An efficient one-pot synthetic approach to access a variety of 3-(indol-3-yl)quinoxalin-2-ones from various quinoxalin 2-ones and very wide scope of indoles through TfOH-catalyzed Friedel-Crafts type coupling reaction in DMF has been developed as mentioned in this paper.