Z
Zhi-Jun Wu
Researcher at Chinese Academy of Sciences
Publications - 130
Citations - 3434
Zhi-Jun Wu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 31, co-authored 130 publications receiving 3174 citations. Previous affiliations of Zhi-Jun Wu include University of Science and Technology of China & Southwest University.
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Journal ArticleDOI
Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine
TL;DR: The first enantioselective organocatalytic two- and three-component reactions via a domino Knoevenagel/Michael/cyclization sequence with cupreine as catalyst have been developed and will provide promising candidates for chemical biology and drug discovery.
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Highly enantioselective oxidative couplings of 2-naphthols catalyzed by chiral bimetallic oxovanadium complexes with either oxygen or air as oxidant.
Qi-Xiang Guo,Zhi-Jun Wu,Zhibin Luo,Quan-Zhong Liu,Jian-Liang Ye,Shi-Wei Luo,L.-F. Cun,Liu-Zhu Gong +7 more
TL;DR: Kinetic studies, the cross-coupling reaction, and HRMS spectral studies on the reaction have been carried out and illustrate that two vanadium(V) species are both involved in catalysis and that the coupling reaction undergoes a radical-radical mechanism in an intramolecular manner.
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Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters
TL;DR: The first example of a direct catalytic asymmetric intermolecular aldol reaction of 3-isothiocyanato oxindoles to simple ketones with bifunctional thiourea-tertiary amine as catalyst is reported.
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Asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and 3-nitroindoles with amino-thiocarbamate catalysts: enantioselective synthesis of polycyclic spirooxindoles.
Jian-Qiang Zhao,Ming-Qiang Zhou,Zhi-Jun Wu,Zhen-Hua Wang,Deng-Feng Yue,Xiao-Ying Xu,Xiao-Mei Zhang,Wei-Cheng Yuan +7 more
TL;DR: An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and 3-nitroindoles has been disclosed and a wide range of enantioenriched polycyclic spirooxindoles, containing three contiguous chiral centers with two of them having quaternary stereocenters are obtained.
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Organocatalytic Asymmetric Michael Addition of Pyrazolin-5-ones to Nitroolefins with Bifunctional Thiourea: Stereocontrolled Construction of Contiguous Quaternary and Tertiary Stereocenters
TL;DR: The first organocatalytic diastereo- and enantioselective Michael addition reaction of 4-substituted-pyrazolin-5-ones to nitroolefins has been developed with a chiral bifunctional thiourea as organoc atalyst.