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Yannick Jeanson

Researcher at Paul Sabatier University

Publications -  15
Citations -  472

Yannick Jeanson is an academic researcher from Paul Sabatier University. The author has contributed to research in topics: Adipose tissue & White adipose tissue. The author has an hindex of 7, co-authored 14 publications receiving 367 citations. Previous affiliations of Yannick Jeanson include University of Toulouse & Centre national de la recherche scientifique.

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Browning of White Adipose Cells by Intermediate Metabolites:An Adaptive Mechanism to Alleviate Redox Pressure

TL;DR: It is demonstrated that lactate, an important metabolic intermediate, induces browning of murine white adipose cells with expression of functional UCP1, and that the lactate effect on Ucp1 is mediated by intracellular redox modifications as a result of lactate transport through monocarboxylate transporters.
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Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice.

TL;DR: In this paper, the effect of coenzyme Q (Q) on ob/ob mice treated or not with thiazolidinedione (TZD) was determined, and cotreatment with Rosiglitazone and Q improved metabolic parameters and prevented TZD increase in body weight and adiposity.
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Regionalization of browning revealed by whole subcutaneous adipose tissue imaging.

TL;DR: White and brown adipose tissues play a major role in the regulation of metabolic functions and there is no data available on possible heterogeneity within an adipose depot.
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A New Role for Browning as a Redox and Stress Adaptive Mechanism

TL;DR: The aim of this review is to summarize the current knowledge concerning brown adipocytes and the browning process and also to explore unexpected putative role(s) for these cells.
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Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway

TL;DR: It is demonstrated that lactate regulates Fgf21 expression through a NADH/NAD-independent pathway, but requires active p38-MAPK (mitogen activated protein kinase) signalling, and that this effect is not restricted to lactate as additional metabolites including pyruvate and ketone bodies also activated the FGF21 stress response.