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Yaping Ju
Researcher at University of Southern California
Publications - 13
Citations - 227
Yaping Ju is an academic researcher from University of Southern California. The author has contributed to research in topics: NOD mice & Cathepsin S. The author has an hindex of 7, co-authored 12 publications receiving 142 citations. Previous affiliations of Yaping Ju include Shanghai Jiao Tong University.
Papers
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Journal ArticleDOI
Preparation of Laponite Bioceramics for Potential Bone Tissue Engineering Applications
Chuanshun Wang,Shige Wang,Kai Li,Yaping Ju,Jipeng Li,Yongxing Zhang,Jinhua Li,Xuanyong Liu,Xiangyang Shi,Qinghua Zhao +9 more
TL;DR: Most strikingly, alkaline phosphatase activity together with alizarin red staining results reveal that the produced LAP bioceramic is able to induce osteoblast differentiation of rMSCs in growth medium without any inducing factors.
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Bifunctional Elastin-like Polypeptide Nanoparticles Bind Rapamycin and Integrins and Suppress Tumor Growth in Vivo.
Jugal P. Dhandhukia,Pu Shi,Santosh Peddi,Zhe Li,Suhaas Aluri,Yaping Ju,Dab Brill,Wan Wang,Siti M. Janib,Yi-An Lin,Shuanglong Liu,Honggang Cui,J. Andrew MacKay +12 more
TL;DR: The bifunctional nanoparticle demonstrated superior cell target binding and similar drug retention to FSI; however, it enhanced the formulation potency, such that tumor growth was suppressed at a 3-fold lower dose compared to an untargeted FSI-Rapa control.
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Application of advances in endocytosis and membrane trafficking to drug delivery.
TL;DR: This review highlights the molecular basis of internalization pathways most relevant to internalized DDS, and the principal methods used to study each route, and showcases examples of DDS that are internalized by each route and reviews the general effects of biophysical properties of D DS on the internalization efficiency.
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Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren's Syndrome.
Wannita Klinngam,Srikanth Reddy Janga,Changrim Lee,Yaping Ju,Frances Yarber,Mihir Shah,Hao Guo,Dandan Wang,J. Andrew MacKay,Maria C. Edman,Sarah F. Hamm-Alvarez +10 more
TL;DR: It is suggested that CTSS inhibitors administered either topically or systemically can mitigate aspects of the ocular manifestations of SS.
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Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren’s Syndrome
TL;DR: Tear CTSS activity is elevated with other early disease indicators, suggesting potential as an early stage biomarker for SS.