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Xiangyang Shi
Researcher at Donghua University
Publications - 527
Citations - 26639
Xiangyang Shi is an academic researcher from Donghua University. The author has contributed to research in topics: Dendrimer & Medicine. The author has an hindex of 79, co-authored 470 publications receiving 22028 citations. Previous affiliations of Xiangyang Shi include University of Michigan & Max Planck Society.
Papers
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Journal ArticleDOI
Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport.
Seungpyo Hong,Anna U. Bielinska,Almut Mecke,Balazs Keszler,James L. Beals,Xiangyang Shi,Lajos P. Balogh,Bradford G. Orr,James R. Baker,Mark M. Banaszak Holl +9 more
TL;DR: A hole formation mechanism is consistent with the observations of dendrimer internalization, cytosolic proteins can diffuse out of the cell via these holes, and dye molecules can be detected diffusing into the cell or out ofThe cell through the same membrane holes.
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Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery.
TL;DR: This paper presents a meta-analyses of the chiral stationary phase replacement process and its applications in bioreactor engineering and nanofiltration .
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PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography
Chen Peng,Linfeng Zheng,Qian Chen,Mingwu Shen,Rui Guo,Han Wang,Xueyan Cao,Guixiang Zhang,Xiangyang Shi,Xiangyang Shi +9 more
TL;DR: The designed PEGylated Au DENPs can be used as a promising contrast agent with enhanced biocompatibility for CT imaging of various biological systems, especially in cancer diagnosis.
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Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors
TL;DR: This study demonstrates a unique multifunctional theranostic nanoplatform for multi-mode imaging and photothermal therapy of tumors, which may find applications in theranostics of different types of cancer.
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Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging.
Xiangyang Shi,Suhe Wang,Sasha Meshinchi,Mary Van Antwerp,Xiangdong Bi,Inhan Lee,James R. Baker +6 more
TL;DR: In vitro studies show that the FA- and FI-modified Au DENPs can specifically bind to KB cells that overexpress high-affinity folate receptors and they are internalized dominantly into lysosomes of target cells within 2 h.