Showing papers by "Yasunori Sohara published in 2001"
TL;DR: Pulmonary gangliocytic paraganglioma is similar to that in the duodenum, and is a hamartomatous proliferation of epithelial endocrine and neuronal cells of the bronchus.
Abstract: The authors report a case of gangliocytic paraganglioma of the lung, which has not yet been described in a pulmonary neoplasm. A 75-year-old man underwent right middle and lower lobe lobectomy. A slightly yellowish mass was located at the bifurcation between the lower and middle lobe bronchus, protruding into the truncus intermedius. The neoplastic cells were composed of three cellular elements: uniform endocrine cells in a Zellballen arrangement, large ganglion-like cells within the nests of endocrine cells, and spindle-shaped cells arranged in streams to surround the nests. Each component exhibited the characteristic immunohistochemical properties, which were similar to those of the corresponding neuroendocrine neoplasms: Endocrine cells were positive for CAM 5.2, chromogranin A, and synaptophysin, like carcinoid tumor; ganglion-like cells were positive only for neurofilament, like ganglioneuroma; and spindle-shaped cells were positive for neurofilament and S-100 protein, like paraganglioma. These results agreed with those in gangliocytic paraganglioma of the duodenum. Pulmonary gangliocytic paraganglioma is similar to that in the duodenum, and is a hamartomatous proliferation of epithelial endocrine and neuronal cells of the bronchus.
50 citations
TL;DR: Aggressive pulmonary resection in chronic necrotizing pulmonary aspergillosis should be considered when patients have prolonged illness or frequent hemoptysis, especially in cases involving a large residual pleural cavity on the right side.
25 citations
TL;DR: A rare case of a 50-year-old man with signs of right heart failure due to localized pericarditis that was secondary to implantation of an artificialPericardial patch 25 years prior following pericardsectomy for constrictive pericARDitis is reported.
Abstract: We report a rare case of a 50-year-old man with signs of right heart failure due to localized pericarditis that was secondary to implantation of an artificial pericardial patch 25 years prior following pericardectomy for constrictive pericarditis. The patient's clinical symptoms resolved completely in the 3 years following patch removal.
15 citations
TL;DR: The controller presents a major obstacle in the development of the rotary blood pump as a left ventricular assist device (LVAD) and the H-Q curve was a loop that changed, depending on LV contractility under pulsatile LV conditions.
Abstract: The controller presents a major obstacle in the development of the rotary blood pump as a left ventricular assist device (LVAD). Clinically, LVAD flow is a good indicator in the regulation of circulatory conditions and pump flow changes, depending on pump preload and afterload. Many investigators have tried estimating pump flow by referencing the motor current. There have been pitfalls in in vitro experimental settings, however. Using a test loop with a pneumatically driven LV chamber and a centrifugal pump as an LVAD, we monitored pump flow and pressure head to evaluate the pump performance curve (H-Q curve). Under pulsatile LV conditions, the H-Q curve was a loop that changed, depending on LV contractility. The pneumatically driven LV chamber cannot mimic the Starling phenomenon, so the developed LV pressure does not change according to the LV preload. Rotary pump flow estimation is the most effective control method. In pulsatile conditions, however, the H-Q curve is a loop that changes under various LV contractility conditions, complicating determination of linear equation for calculating flow. In addition, the LV chamber in the test loop cannot mimic native heart contractility as described by Starling's law. This finding can lead to a misanalysis of the H-Q curve under pulsatile conditions.
11 citations
TL;DR: A rare case of long segmental laryngotracheal stenosis following inhalation burn injury with progressive stridor and dyspnea necessitating tracheostomy is reported.
Abstract: We report a rare case of long segmental laryngotracheal stenosis following inhalation burn injury. The patient presented 2 months after his injury with progressive stridor and dyspnea necessitating tracheostomy. A computed tomographic scan of the neck revealed stenosis extending from the vocal cords to the top of the sternum. Repair was successfully carried out with multiple surgical procedures employing hinge-flap closure tented with autogenous tissue.
6 citations
Journal Article•
TL;DR: It is emphasized that intrapulmonary lymph nodes should be taken into consideration in differential diagnoses of small nodular lesions in the lung, and thoracoscopy is useful in making a definite diagnosis if peripheral pulmonary lesions cannot be diagnosed.
Abstract: We encountered 12 cases (9 men, 3 women) of intrapulmonary lymph nodes, discovered by chest radiography or chest CT and identified by thoracoscopic lung biopsy (in 10 cases), open lung biopsy (1 case) or lobectomy (1 case). We also studied the literature related to intrapulmonary lymph nodes in Japanese. Many intrapulmonary lymph nodes were found in the lower lung field, few in the upper lung field. All intrapulmonary lymph nodes were spherical and were located under the pleura, but we were not able in some cases to differentiate them from malignancies by the CT scanfindings. We could not diagnose them or rule out malignancy before surgery. Pathological findings revealed that all of them showed anthracosis. Silicotic changes were found in three cases. We consider that thoracoscopy is useful in making a definite diagnosis if peripheral pulmonary lesions cannot be diagnosed. We emphasize that intrapulmonary lymph nodes should be taken into consideration in differential diagnoses of small nodular lesions in the lung.
3 citations
Journal Article•
TL;DR: A sixty-one-year-old man admitted to the authors' hospital because of a right lung tumor shadow was treated with an induction chemotherapy followed by right middle and lower lobectomy with a mediastinal nodal dissection.
Abstract: A sixty-one-year-old man was admitted to our hospital because of a right lung tumor shadow. He had been diagnosed as having sarcoidosis at the age of fifty-seven. He was newly diagnosed as having squamous cell carcinoma by trans bronchial biopsy. He was treated with an induction chemotherapy (cisplatin 80 mg/m2 + vinorelbine 20 mg/m2) followed by right middle and lower lobectomy with a mediastinal nodal dissection, because the stage of his carcinoma was cT2N2M0. Resected lung tissue showed the disappearance of cancer cells. Dissected mediastinal and hilar lymph nodes showed many sarcoid granulomas. Cisplatin combined with vinorelbine might be an effective chemotherapy for non-small cell lung carcinoma.
2 citations
TL;DR: Chinese New Year Honours: 胸部X線写真にて左側胸水を認め, 炎症反応高値, 上海水検査では好中球が97%より, 膿胸を考えた.
Abstract: 症例は55歳, 男性.咳嗽と発熱を主訴に入院. 胸部X線写真にて左側胸水を認め, 炎症反応高値, 胸水検査では好中球が97%より, 膿胸を考えた. 抗生剤投与, 胸腔ドレナージを開始したが改善がみられず, 外科的に左胸膜剥皮術を施行した.術後病理組織では悪性胸膜中皮腫, 肉腫型と診断された. 悪性胸膜中皮腫では発熱, 炎症反応高値を伴うものもあり, 胸膜の肥厚を伴う膿胸などとの鑑別を慎重に行う必要があるものと考えられた.
1 citations
TL;DR: It is confirmed that clear cell carcinoma has been identified in patients with prior history of atypical papillomavirus.
Abstract: 右上葉気管支内腔に限局し, 充満性に発育した腎癌の転移性気道腫瘍に対し右上葉管状切除術を施行した1例を報告する.症例は, 53歳男性で, 喀血, 腫瘤の喀出を主訴に外来受診した.既往歴では, 8年前に左腎癌にて腎摘出術を行なっていた.気管支鏡では, 疣贅状の腫瘤が右上幹入口部を完全に閉塞し, 一部主幹に突出していた.喀出した腫瘤の組織診で, 腎癌の転移性気道腫瘍と診断した.全身検索の結果, 局所再発, 多臓器転移を認めず右肺上葉管状切除術, 縦隔リンパ節郭清を施行した.病理組織では, clear cell carcinomaが右B1, B2の気管支内腔に限局し, 充満するように発育していた.術後5年再発徴候は認められない.転移性気道腫瘍としては, 腎癌は多く報告されているが本例の如く, 肺実質内への侵襲がなく気道内腔に広汎に発育した特異な転移形式を認めた症例は珍しく文献的考察を加え報告する.