Y
Yasushi Seo
Researcher at Kobe University
Publications - 52
Citations - 1206
Yasushi Seo is an academic researcher from Kobe University. The author has contributed to research in topics: Hepatitis B virus & Hepatocellular carcinoma. The author has an hindex of 17, co-authored 52 publications receiving 1099 citations.
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High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases.
TL;DR: Results indicate that PRL-3 expression in colorectal cancers may contribute to the establishment of liver metastasis, particularly at the step in which cancer cells leave the circulation to extravasate into the liver tissue.
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Growth Hormone Reverses Nonalcoholic Steatohepatitis in a Patient With Adult Growth Hormone Deficiency
Yutaka Takahashi,Keiji Iida,Kentaro Takahashi,Shiro Yoshioka,Hidenori Fukuoka,Ryoko Takeno,Mari Imanaka,Hitoshi Nishizawa,Michiko Takahashi,Yasushi Seo,Yoshitake Hayashi,Takuma Kondo,Yasuhiko Okimura,Hidesuke Kaji,Riko Kitazawa,Sohei Kitazawa,Kazuo Chihara +16 more
TL;DR: It is suggested that GH plays an essential role in the metabolic and redox regulation in the liver and the abnormal lipid profile concomitant with a marked reduction in oxidative stress.
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Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy.
Hitoshi Nishizawa,Genzo Iguchi,Ayumi Murawaki,Hidenori Fukuoka,Yoshitake Hayashi,Hidesuke Kaji,Masaaki Yamamoto,Kentaro Suda,Michiko Takahashi,Yasushi Seo,Yoshihiko Yano,Riko Kitazawa,Sohei Kitazawa,Masafumi Koga,Yasuhiko Okimura,Kazuo Chihara,Yutaka Takahashi +16 more
TL;DR: The effect of GH replacement therapy suggests that the NAFLD is predominantly attributable to GHD, and adult hypopituitary patients with GHD demonstrated a highNAFLD prevalence.
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Heterogeneous expression of claudin-4 in human colorectal cancer: decreased claudin-4 expression at the invasive front correlates cancer invasion and metastasis.
Junya Ueda,Shuho Semba,Hideki Chiba,Norimasa Sawada,Yasushi Seo,Masato Kasuga,Hiroshi Yokozaki +6 more
TL;DR: It is suggested that disruption of claudin-4-mediated TJ construction enhances cancer cell invasion and metastasis in human CRC and might be a good biomarker for diagnosing the risk of distant metastasis.
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Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport.
Yuki Kawano,Shin Nishiumi,Shinwa Tanaka,Kentaro Nobutani,Akira Miki,Yoshihiko Yano,Yasushi Seo,Hiromu Kutsumi,Hitoshi Ashida,Takeshi Azuma,Masaru Yoshida +10 more
TL;DR: AHR activation induces hepatic microvesicular steatosis by increasing the expression level of FAT and the mRNA level of peroxisome proliferator-activated receptor (PPAR) α was increased in the livers of 3MC-treated mice.