Kazuo Chihara

TL;DR: Ghrelin was identified in the stomach as an endogenous ligand specific for the growth hormone secretagogue receptor (GHS-R) and its findings raise the possibility that ghrelin modulates insulin activities in humans.

TL;DR: Chemerin potentiated insulin‐stimulated glucose uptake concomitant with enhanced insulin signaling in the 3T3‐L1 adipocytes and established that chemerin is a novel adipokine that regulates adipocyte function.

TL;DR: It is suggested that GH plays an essential role in the metabolic and redox regulation in the liver and the abnormal lipid profile concomitant with a marked reduction in oxidative stress.

TL;DR: It is demonstrated that PTH stimulates osteoblast beta-catenin levels via Smad3, and that both PKA and PKC pathways are involved, which is likely to be involved in the antiapoptotic actions of PTH by acting through Smad 3 in osteoblasts.

TL;DR: It was found that mineralization of the mouse osteoblastic MC3T3-E1 cells was increased when the cells were exposed to high calcium or a specific CaR activator, NPS-R467, which suggests that the CaR may be involved in osteoblast differentiation.