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Yee-Ling Lai
Researcher at National Environment Agency
Publications - 15
Citations - 1192
Yee-Ling Lai is an academic researcher from National Environment Agency. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 13, co-authored 14 publications receiving 1073 citations.
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Journal ArticleDOI
Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness.
Lukas B. Tanner,Mark Schreiber,Jenny G. Low,Adrian Ong,Thomas Tolfvenstam,Yee-Ling Lai,Lee Ching Ng,Yee Sin Leo,Le Thi Puong,Subhash G. Vasudevan,Cameron P. Simmons,Martin L. Hibberd,Eng Eong Ooi +12 more
TL;DR: This study shows a proof-of-concept that decision algorithms using simple clinical and haematological parameters can predict diagnosis and prognosis of dengue disease, a finding that could prove useful in disease management and surveillance.
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Cost-Effective Real-Time Reverse Transcriptase PCR (RT-PCR) To Screen for Dengue Virus followed by Rapid Single-Tube Multiplex RT-PCR for Serotyping of the Virus
Yee-Ling Lai,Youne-Kow Chung,Hwee Cheng Tan,Hoon-Fang Yap,Grace Yap,Eng Eong Ooi,Lee Ching Ng +6 more
TL;DR: Validation of the assays with local clinical samples collected from 2004 to 2006 revealed that there was an 88% positive correlation between virus isolation and RT-PCR with regard to dengue virus detection and a 100% correlation with seroconversion in subsequent samples.
Journal Article
Early Dengue infection and outcome study (EDEN) - study design and preliminary findings.
Jenny G. Low,Eng Eong Ooi,Thomas Tolfvenstam,Yee Sin Leo,Martin L. Hibberd,Lee Ching Ng,Yee-Ling Lai,Grace Yap,Chenny Li,Subhash G. Vasudevan,Adrian Ong +10 more
TL;DR: The duration of illness and prolonged symptom duration in 9% of the subjects indicate that the burden of dengue illness is substantially different from other non-dengue febrile illness in the study cohort, and highlights the paucity of early prognostic markers for d Dengue fever in adults.
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Entomologic and Virologic Investigation of Chikungunya, Singapore
Lee Ching Ng,Li Kiang Tan,Cheong Huat Tan,Sharon S.Y. Tan,Hapuarachchige Chanditha Hapuarachchi,Kwoon-Yong Pok,Yee-Ling Lai,Sai-Gek Lam-Phua,Göran Bucht,Raymond T. P. Lin,Yee Sin Leo,Boon Hian Tan,Hwi-Kwang Han,Peng-Lim Ooi,Lyn James,Seow-Poh Khoo +15 more
TL;DR: Data from longitudinal analyses can be useful in the design and implementation of control strategies and should be considered in the development of new control strategies.
Journal ArticleDOI
Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore.
Hapuarachchige Chanditha Hapuarachchi,K.B.A.T. Bandara,S. D. M. Sumanadasa,Menaka Hapugoda,Yee-Ling Lai,Kim-Sung Lee,Li Kiang Tan,Raymond T. P. Lin,Lisa F. P. Ng,Göran Bucht,Wimaladharma Abeyewickreme,Lee Ching Ng +11 more
TL;DR: The evolutionary network based on E1 gene sequences indicated the acquisition of an alanine to valine 226 substitution (E1-A226V) by virus strains of the Indian sublineage as a key evolutionary event that contributed to the transmission and spatial distribution of CHIKV in the region.