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Yeon-Kyung Choi
Researcher at Kyungpook National University
Publications - 33
Citations - 1199
Yeon-Kyung Choi is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Medicine & Glutamine. The author has an hindex of 14, co-authored 24 publications receiving 851 citations. Previous affiliations of Yeon-Kyung Choi include Kyungpook National University Hospital.
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Journal ArticleDOI
Serum irisin levels in new-onset type 2 diabetes
Yeon-Kyung Choi,Mi-Kyung Kim,Kwi Hyun Bae,Hyun-Ae Seo,Ji-Yun Jeong,Won-Kee Lee,Jung-Guk Kim,Inkyu Lee,Keun-Gyu Park +8 more
TL;DR: It is found that serum irisin levels were decreased in T1D patients and inversely associated with newly diagnosed T2D, suggesting that irisin may play a crucial role in glucose intolerance and T2 D.
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Targeting Glutamine Metabolism for Cancer Treatment
Yeon-Kyung Choi,Keun-Gyu Park +1 more
TL;DR: An overview of the role of glutamine metabolism in cancer cell survival and growth is provided and the potential therapeutic approaches of targeting glutamines metabolism for the treatment of numerous types of cancer are summarized.
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Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity
Jun-Kyu Byun,Jun-Kyu Byun,Mihyang Park,Seunghyeong Lee,Jae Won Yun,Jaebon Lee,Jae Sun Kim,Sung Jin Cho,Hui-Jeon Jeon,Inkyu Lee,Inkyu Lee,Yeon-Kyung Choi,Yeon-Kyung Choi,Keun-Gyu Park,Keun-Gyu Park +14 more
TL;DR: It is reported that limiting glutamine metabolism in cancer cells bolsters the effectiveness of anti-programmed death ligand-1 (PD-L1) antibody and suggested that co-targeting of glutamines metabolism and PD- L1 represents a promising therapeutic approach.
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Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis
Yun-A Jung,Yeon-Kyung Choi,Gwon-Soo Jung,Hye-Young Seo,Hye-Soon Kim,Byoung Kuk Jang,Jung-Guk Kim,Inkyu Lee,Mi-Kyung Kim,Keun-Gyu Park +9 more
TL;DR: Sitagliptin attenuated MCD diet-induced hepatic steatosis, inflammation, and fibrosis in mice through amelioration of mechanisms responsible for the development of NASH, including CD36 expression, NF-κB activation, ER stress, CYP2E1 expression, and lipid peroxidation.
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A Positive Feedback Loop between Sestrin2 and mTORC2 Is Required for the Survival of Glutamine-Depleted Lung Cancer Cells
Jun-Kyu Byun,Yeon-Kyung Choi,Ji-Hyun Kim,Ji Yun Jeong,Hui-Jeon Jeon,Mi-Kyung Kim,Ilseon Hwang,Shin-Yup Lee,You Mie Lee,Inkyu Lee,Keun-Gyu Park +10 more
TL;DR: In this article, Sestrin2 and mTORC2 are upregulated in glutamine-depleted lung cancer cells, which is necessary for the survival of the cells.