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Yevgenya Grinblat
Researcher at University of Wisconsin-Madison
Publications - 30
Citations - 1568
Yevgenya Grinblat is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Zebrafish & Forebrain. The author has an hindex of 20, co-authored 28 publications receiving 1482 citations. Previous affiliations of Yevgenya Grinblat include Harvard University & Massachusetts Institute of Technology.
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Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells.
TL;DR: Copper and cadmium, when added to the growth medium of Drosophila Schneider's line 2 cells, can produce a 30-100 fold induction of metallothionein mRNA levels, and a chimeric gene containing the metallothsionein promoter shows a similar induction when transformed into the cells.
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Determination of the zebrafish forebrain: induction and patterning
TL;DR: Using in vitro explant assays, it is shown that forebrain induction has occurred even earlier, by the onset of gastrulation, and that a wide area of dorsal mesendoderm is required for its patterning.
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Anteroposterior patterning in the zebrafish, Danio rerio: an explant assay reveals inductive and suppressive cell interactions.
TL;DR: The first extended culture system for analysing zebrafish (Danio rerio) embryogenesis is reported, with which neural induction and anteroposterior patterning are demonstrated and data suggest that anteroplosterior patterns in the zebra fish is a multi-step process.
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Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA
Felicite K. Noubissi,Srikanta Goswami,Nicholas A. Sanek,Kazuyuki Kawakami,Toshinari Minamoto,Amy R. Moser,Yevgenya Grinblat,Vladimir S. Spiegelman +7 more
TL;DR: A novel mechanism by which Wnt signaling pathway stimulates the transcriptional output of Hedgehog signaling, causing an elevation of GLI1 expression and transcriptional activity is identified and seems to be important to several functions of Wnt, including survival and proliferation of colorectal cancer cells.
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MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein.
Srikanta Goswami,Rohinton Tarapore,Jessica J. TeSlaa,Yevgenya Grinblat,Vijayasaradhi Setaluri,Vladimir S. Spiegelman +5 more
TL;DR: It is shown that melanoma cells favor the expression of MITF mRNA with shorter 3′-UTR, which is regulated by microRNA, miR-340, and this interplay between RNA-binding protein and miRNA describes the important mechanism of regulation ofMITF in melanocytes and malignant melanomas.